EAF1 and ELL2

Number of citations of the paper that reports this interaction (PubMedID 11418481)
29

Data Source:
HPRD (in vivo)

		EAF1	ELL2
Description		ELL associated factor 1	elongation factor for RNA polymerase II 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Body Nuclear Speck Super Elongation Complex Intracellular Membrane-bounded Organelle Intercellular Bridge	Nucleoplasm Transcription Elongation Factor Complex
	Molecular Function	Transcription Elongation Regulator Activity Protein Binding	Protein Binding
	Biological Process	Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated	Transcription Elongation From RNA Polymerase II Promoter SnRNA Transcription By RNA Polymerase II
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS			Albumin-globulin ratio ( 29403010) B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Body mass index ( 26426971) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) IgA levels ( 28628107) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Mean corpuscular hemoglobin ( 32888494) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Non-albumin protein levels ( 29403010) Serum total protein level ( 23022100) Telomere length ( 30185882)
Interacting Genes		53 interacting genes: AP2M1 APP ARID4B BEND7 BHLHB9 CCDC150 CCDC33 CEP70 CEP76 DNTTIP1 DPPA4 ELL ELL2 ELL3 FAM228A GADD45GIP1 GAS8 GCSAML GOLGA6L9 GRHL3 GTF2H1 GTF2H4 HOMER3 HSF2BP KEAP1 KIAA1328 MAB21L3 MIPOL1 NUMB PAX6 PICK1 PIH1D1 PSME3 RYBP SDCBP SEMG1 SH3RF1 SRP14 STAC3 TCEA2 TFCP2 TFPT TLE5 TNFAIP8 TNNI1 TRAF2 TRIM62 VAX1 YAF2 ZBTB14 ZNF143 ZNF202 ZNF620	7 interacting genes: AFF4 AQP2 CASK EAF1 EXOC8 PRKAB2 SIAH1
Entrez ID		85403	22936
HPRD ID		12209	11798
Ensembl ID		ENSG00000144597	ENSG00000118985
Uniprot IDs		Q96JC9	O00472 Q59FW6 Q7Z656
PDB IDs			2E5N 5JW9
Enriched GO Terms of Interacting Partners?
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