CEP89 and NCS1

Number of citations of the paper that reports this interaction (PubMedID 26638075)
175

Data Source:
BioGRID (proximity labelling technology, two hybrid)

		CEP89	NCS1
Description		centrosomal protein 89	neuronal calcium sensor 1
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Mitochondrial Intermembrane Space Centrosome Centriole Cytosol Plasma Membrane Motile Cilium Synapse Ciliary Transition Fiber Non-motile Cilium	Cytoplasm Golgi Apparatus Plasma Membrane Postsynaptic Density Dendrite Dense Core Granule Intracellular Membrane-bounded Organelle Calyx Of Held Perinuclear Region Of Cytoplasm Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol
	Molecular Function	Protein Binding	Magnesium Ion Binding Voltage-gated Calcium Channel Activity Calcium Ion Binding Protein Binding Protein Kinase Binding Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels
	Biological Process	Mitochondrion Organization Chemical Synaptic Transmission Cilium Assembly Non-motile Cilium Assembly	Regulation Of Neuron Projection Development Positive Regulation Of Exocytosis Phosphatidylinositol-mediated Signaling Calcium Ion Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Synaptic Vesicle Exocytosis
Pathways		Anchoring of the basal body to the plasma membrane
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 31152163) Estimated glomerular filtration rate in non-diabetics ( 31451708) Longevity (age >90th survival percentile) ( 31413261) Serum metabolite levels ( 33031748) Urate levels ( 31578528)	Alzheimer's disease (cognitive decline) ( 23535033) Tuberculosis ( 30713548)
Interacting Genes		3 interacting genes: FXR1 NCS1 PICK1	28 interacting genes: C1QTNF2 CDSN CEP89 CREM CTAG1A CTAG1B DRD2 DRD3 DRD5 DTX2 EXOSC2 FZD7 GRK2 IL1RAPL1 KCND2 LY6G6D MEOX2 MIEF2 NBL1 OXER1 PI4KB PRDM4 RNASEH1 SFTPA2 SIGLEC9 SPP1 SPRED2 ZC3H10
Entrez ID		84902	23413
HPRD ID		08601	04500
Ensembl ID		ENSG00000121289	ENSG00000107130
Uniprot IDs		Q96ST8	A0A024R8B2 P62166
PDB IDs			1G8I 2LCP 4GUK 5O9S 6QI4
Enriched GO Terms of Interacting Partners?
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