NCS1 and PI4KB

Number of citations of the paper that reports this interaction (PubMedID 11526106)
56

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		NCS1	PI4KB
Description		neuronal calcium sensor 1	phosphatidylinositol 4-kinase beta
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Plasma Membrane Postsynaptic Density Dendrite Dense Core Granule Intracellular Membrane-bounded Organelle Calyx Of Held Perinuclear Region Of Cytoplasm Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol	Golgi Membrane Cytoplasm Mitochondrial Outer Membrane Endosome Cytosol Membrane Rough Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Magnesium Ion Binding Voltage-gated Calcium Channel Activity Calcium Ion Binding Protein Binding Protein Kinase Binding Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels	1-phosphatidylinositol 4-kinase Activity Protein Binding ATP Binding Phosphatidylinositol Kinase Activity 14-3-3 Protein Binding
	Biological Process	Regulation Of Neuron Projection Development Positive Regulation Of Exocytosis Phosphatidylinositol-mediated Signaling Calcium Ion Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Synaptic Vesicle Exocytosis	Phosphatidylinositol Biosynthetic Process Receptor-mediated Endocytosis Signal Transduction Phosphorylation Phosphatidylinositol Phosphate Biosynthetic Process Phosphatidylinositol-mediated Signaling
Pathways			Synthesis of PIPs at the Golgi membrane
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate	Fostamatinib
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Tuberculosis ( 30713548)	Body mass index ( 26426971) Gut microbiota (functional units) ( 27694959)
Interacting Genes		28 interacting genes: C1QTNF2 CDSN CEP89 CREM CTAG1A CTAG1B DRD2 DRD3 DRD5 DTX2 EXOSC2 FZD7 GRK2 IL1RAPL1 KCND2 LY6G6D MEOX2 MIEF2 NBL1 OXER1 PI4KB PRDM4 RNASEH1 SFTPA2 SIGLEC9 SPP1 SPRED2 ZC3H10	5 interacting genes: MYCBP2 NCS1 YWHAB YWHAG YWHAQ
Entrez ID		23413	5298
HPRD ID		04500	11805
Ensembl ID		ENSG00000107130	ENSG00000143393
Uniprot IDs		A0A024R8B2 P62166	A0A0B4J1S8 Q9UBF8
PDB IDs		1G8I 2LCP 4GUK 5O9S 6QI4	2N73 4D0L 4D0M 4WAE 4WAG 5C46 5C4G 5EUQ 5FBL 5FBQ 5FBR 5FBV 5FBW 5LX2 5NAS 6GL3
Enriched GO Terms of Interacting Partners?
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