MFSD14B and TMEM119

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MFSD14B	TMEM119
Description		major facilitator superfamily domain containing 14B	transmembrane protein 119
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Transmembrane Transporter Activity	Molecular_function
	Biological Process	Transmembrane Transport	Osteoblast Differentiation Positive Regulation Of Protein Phosphorylation Endochondral Ossification Spermatogenesis Positive Regulation Of Gene Expression Negative Regulation Of Myotube Differentiation Positive Regulation Of Bone Mineralization Biomineral Tissue Development Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Bone Resorption Spermatid Differentiation Positive Regulation Of Bone Development
Pathways
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 30054594 29235454) Optic disc size ( 31809533) Refractive error ( 32231278)
Interacting Genes		76 interacting genes: ADIPOQ AGPAT3 AGPAT4 ARL6IP1 ATP13A1 BNIP3 C14orf180 C4orf3 CCL4L2 CFHR5 CLDN4 CMTM3 COMT CSGALNACT2 CTSA CYB5B CYBC1 DEFB127 DNAJC30 EMC6 ERG28 ETS2 FKBP8 FMO1 FUNDC2 GIMAP1 GOSR2 GRM2 KTN1 LAT LEPROTL1 LPCAT2 LRP10 MGLL MS4A1 NAT8 ORMDL1 PEX16 PKMYT1 PRRT2 RNF24 SACM1L SCD SERP1 SERP2 SLC25A46 SLC39A9 SLC66A2 SMAGP STX3 TECR THSD7B TIMMDC1 TMBIM6 TMEM119 TMEM167B TMEM176A TMEM19 TMEM208 TMEM229B TMEM239 TMEM31 TMX2 TPRG1 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 USE1 YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC24 ZFPL1	7 interacting genes: AQP6 CERS4 MFSD14B ODF4 SLC10A1 SLC10A6 TSHR
Entrez ID		84641	338773
HPRD ID		07869	11260
Ensembl ID		ENSG00000148110	ENSG00000183160
Uniprot IDs		Q5SR56	Q4V9L6
PDB IDs
Enriched GO Terms of Interacting Partners?
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