MFSD14B and ETS2

		MFSD14B	ETS2
Description		major facilitator superfamily domain containing 14B	ETS proto-oncogene 2, transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Transmembrane Transporter Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding Glucocorticoid Receptor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transmembrane Transport	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Ectodermal Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Mesoderm Development Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Primitive Streak Formation
Pathways			Oncogene Induced Senescence
Drugs
Diseases
GWAS			Adult body size ( 32376654) Body mass index ( 25673413) Body size at age 10 ( 32376654) C-reactive protein levels ( 30388399) Central corneal thickness ( 32528159) Eye morphology ( 29921221) Fibrinogen levels ( 28107422) Finger osteoarthritis severity (hand Klsum) ( 33055079) Fractures ( 30158200) Intraocular pressure ( 29617998) Non-small cell lung cancer (survival) ( 21079520) Periodontitis (Mean PAL) ( 24024966) Schizophrenia ( 30285260) Serum alkaline phosphatase levels ( 33547301) TPE interval (response to exercise) ( 32386560)
Interacting Genes		76 interacting genes: ADIPOQ AGPAT3 AGPAT4 ARL6IP1 ATP13A1 BNIP3 C14orf180 C4orf3 CCL4L2 CFHR5 CLDN4 CMTM3 COMT CSGALNACT2 CTSA CYB5B CYBC1 DEFB127 DNAJC30 EMC6 ERG28 ETS2 FKBP8 FMO1 FUNDC2 GIMAP1 GOSR2 GRM2 KTN1 LAT LEPROTL1 LPCAT2 LRP10 MGLL MS4A1 NAT8 ORMDL1 PEX16 PKMYT1 PRRT2 RNF24 SACM1L SCD SERP1 SERP2 SLC25A46 SLC39A9 SLC66A2 SMAGP STX3 TECR THSD7B TIMMDC1 TMBIM6 TMEM119 TMEM167B TMEM176A TMEM19 TMEM208 TMEM229B TMEM239 TMEM31 TMX2 TPRG1 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 USE1 YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC24 ZFPL1	22 interacting genes: CDK10 COP1 CREBBP EP300 ERG ETS1 FOS GATA3 HMGN1 JUN MFSD14B NCOR1 NR3C1 POU5F1 SMARCA4 SPI1 SRA1 SRC STAT5B TDP2 ZFYVE9 ZMYND11
Entrez ID		84641	2114
HPRD ID		07869	01263
Ensembl ID		ENSG00000148110	ENSG00000157557
Uniprot IDs		Q5SR56	P15036
PDB IDs			4BQA 4MHV
Enriched GO Terms of Interacting Partners?
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