TMEM119 and MFSD14B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM119	MFSD14B
Description		transmembrane protein 119	major facilitator superfamily domain containing 14B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Integral Component Of Membrane
	Molecular Function	Molecular_function	Protein Binding Transmembrane Transporter Activity
	Biological Process	Osteoblast Differentiation Positive Regulation Of Protein Phosphorylation Endochondral Ossification Spermatogenesis Positive Regulation Of Gene Expression Negative Regulation Of Myotube Differentiation Positive Regulation Of Bone Mineralization Biomineral Tissue Development Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Bone Resorption Spermatid Differentiation Positive Regulation Of Bone Development	Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 30054594 29235454) Optic disc size ( 31809533) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: AQP6 CERS4 MFSD14B ODF4 SLC10A1 SLC10A6 TSHR	76 interacting genes: ADIPOQ AGPAT3 AGPAT4 ARL6IP1 ATP13A1 BNIP3 C14orf180 C4orf3 CCL4L2 CFHR5 CLDN4 CMTM3 COMT CSGALNACT2 CTSA CYB5B CYBC1 DEFB127 DNAJC30 EMC6 ERG28 ETS2 FKBP8 FMO1 FUNDC2 GIMAP1 GOSR2 GRM2 KTN1 LAT LEPROTL1 LPCAT2 LRP10 MGLL MS4A1 NAT8 ORMDL1 PEX16 PKMYT1 PRRT2 RNF24 SACM1L SCD SERP1 SERP2 SLC25A46 SLC39A9 SLC66A2 SMAGP STX3 TECR THSD7B TIMMDC1 TMBIM6 TMEM119 TMEM167B TMEM176A TMEM19 TMEM208 TMEM229B TMEM239 TMEM31 TMX2 TPRG1 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 USE1 YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC24 ZFPL1
Entrez ID		338773	84641
HPRD ID		11260	07869
Ensembl ID		ENSG00000183160	ENSG00000148110
Uniprot IDs		Q4V9L6	Q5SR56
PDB IDs
Enriched GO Terms of Interacting Partners?
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