TEAD2 and C14orf39

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TEAD2	C14orf39
Description		TEA domain transcription factor 2	chromosome 14 open reading frame 39
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytosol Intracellular Membrane-bounded Organelle TEAD-YAP Complex	Central Element Cellular_component Chromosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding DNA-binding Transcription Factor Activity Protein Binding Disordered Domain Specific Binding Sequence-specific Double-stranded DNA Binding	Molecular_function Protein Binding
	Biological Process	Vasculogenesis Neural Tube Closure Embryonic Heart Tube Morphogenesis Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Notochord Development Hippo Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Paraxial Mesoderm Development Lateral Mesoderm Development Embryonic Organ Development Negative Regulation Of Cell Death Protein-containing Complex Assembly Cellular Response To Retinoic Acid Regulation Of Stem Cell Differentiation	Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Processing Involved In Reciprocal Meiotic Recombination Oogenesis Regulation Of DNA-binding Transcription Factor Activity
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription
Drugs
Diseases
GWAS			Body shape index ( 34021172) Chronotype ( 30696823) Glaucoma ( 30054594) Glaucoma (high intraocular pressure) ( 33627673) Glaucoma (low intraocular pressure) ( 33627673) Glaucoma (primary open-angle) ( 33627673) Gut microbiota (bacterial taxa) ( 27723756) Heel bone mineral density ( 30598549) Height ( 28552196 25282103 23563607) Hip circumference adjusted for BMI ( 28552196 34021172) Macular thickness ( 30535121) Menarche (age at onset) ( 27182965) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		45 interacting genes: AKT1 ARNT AURKA BCL2L15 BECN1 C14orf39 CCND2 CDK4 CDK6 CDKN2A CDKN2B DACH1 EPHA2 FGFR4 FZR1 GLIS1 GLIS2 GNG13 HGF HIF1A INPP5A LATS2 MAP2K3 MAP2K5 MAP3K5 MYC NCOA1 NEDD4 NFIC NSD3 RAF1 RASSF1 RUNX1 SAA2 SOX3 STK11 TERT TP53 TRIM3 USF2 VGLL1 VGLL3 VGLL4 WWTR1 YAP1	5 interacting genes: HPGDS MT1X PRKCH TEAD2 TRIM54
Entrez ID		8463	317761
HPRD ID		03432	08504
Ensembl ID		ENSG00000074219	ENSG00000179008
Uniprot IDs		A0A024QZE2 Q15562	Q8N1H7
PDB IDs		3L15 5DQ8 5DQE 5EMV 5HGU 6CDY 6E5G 6S60 6S64 6S66 6S69 6S6J 6UYB 6UYC 6VAH
Enriched GO Terms of Interacting Partners?
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