PGBD1 and ZNF446

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		PGBD1	ZNF446
Description		piggyBac transposable element derived 1	zinc finger protein 446
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Chromatin Extracellular Space Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Scavenger Receptor Activity Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Endocytosis	Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Hemoglobin levels ( 32327693) Kawasaki disease ( 33106546) Lung cancer ( 28604730) Myopia ( 27182965) Pulse pressure ( 30578418) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545)	Obesity-related traits ( 23251661) Uric acid clearance ( 28095793)
Interacting Genes		12 interacting genes: MEOX2 NR4A1 SCAND1 TRAF2 ZKSCAN4 ZKSCAN7 ZNF446 ZNF496 ZSCAN12 ZSCAN18 ZSCAN22 ZSCAN32	60 interacting genes: ACTN2 ANKRD1 CCNK COPS2 CYSRT1 DGCR6 DGCR6L EHMT2 EVI5 FHL5 FRMD8 FRS3 GOLGA6L9 INCA1 KIFC3 KRT31 KRT34 KRT35 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP3-1 LNX1 LZTS2 MAGOHB MDFI NBPF19 NOTCH2NLA PGBD1 PIN1 REL SCAND1 SIVA1 SUFU TAX1BP1 TRIM27 UBE2I UBE3A ZKSCAN4 ZKSCAN7 ZNF165 ZNF18 ZNF232 ZNF24 ZNF263 ZNF396 ZNF397 ZNF483 ZNF496 ZSCAN12 ZSCAN16 ZSCAN18 ZSCAN21 ZSCAN22 ZSCAN23 ZSCAN29 ZSCAN30 ZSCAN32 ZSCAN9
Entrez ID		84547	55663
HPRD ID		11426	07934
Ensembl ID		ENSG00000137338	ENSG00000083838
Uniprot IDs		Q96JS3	Q8NDK2 Q9NWS9 Q9UFF2
PDB IDs
Enriched GO Terms of Interacting Partners?
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