ZNF446 and ZKSCAN4

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid, two hybrid)

		ZNF446	ZKSCAN4
Description		zinc finger protein 446	zinc finger with KRAB and SCAN domains 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Extracellular Space Nucleus	Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II
Pathways		Generic Transcription Pathway	Generic Transcription Pathway
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Uric acid clearance ( 28095793)	Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Basal metabolic rate ( 31453325) Basal metabolic rate variance ( 31453325) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278) Schizophrenia ( 30285260) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		60 interacting genes: ACTN2 ANKRD1 CCNK COPS2 CYSRT1 DGCR6 DGCR6L EHMT2 EVI5 FHL5 FRMD8 FRS3 GOLGA6L9 INCA1 KIFC3 KRT31 KRT34 KRT35 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP3-1 LNX1 LZTS2 MAGOHB MDFI NBPF19 NOTCH2NLA PGBD1 PIN1 REL SCAND1 SIVA1 SUFU TAX1BP1 TRIM27 UBE2I UBE3A ZKSCAN4 ZKSCAN7 ZNF165 ZNF18 ZNF232 ZNF24 ZNF263 ZNF396 ZNF397 ZNF483 ZNF496 ZSCAN12 ZSCAN16 ZSCAN18 ZSCAN21 ZSCAN22 ZSCAN23 ZSCAN29 ZSCAN30 ZSCAN32 ZSCAN9	23 interacting genes: CABP5 IL36RN LXN MDM4 MEOX2 OGT OSGIN1 PGBD1 PSMA6 SCAND1 TIAM1 TRIM39 ZKSCAN7 ZNF24 ZNF397 ZNF446 ZNF483 ZNF496 ZSCAN20 ZSCAN21 ZSCAN22 ZSCAN30 ZSCAN32
Entrez ID		55663	387032
HPRD ID		07934	15768
Ensembl ID		ENSG00000083838	ENSG00000187626
Uniprot IDs		Q8NDK2 Q9NWS9 Q9UFF2	A0A0S2Z658 B7Z7H3 Q969J2
PDB IDs
Enriched GO Terms of Interacting Partners?
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