SRRM4 and U2AF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SRRM4	U2AF1
Description		serine/arginine repetitive matrix 4	U2 small nuclear RNA auxiliary factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF Complex
	Molecular Function	MRNA Binding Protein Binding Identical Protein Binding	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development Sensory Perception Of Sound RNA Splicing Cell Differentiation Neuron Maturation Regulation Of RNA Splicing	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Facial morphology (factor 3, length of philtrum) ( 28441456) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Photic sneeze reflex ( 27182965) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Stroke ( 32693751)	Blood and toenail selenium levels ( 25343990)
Interacting Genes		30 interacting genes: - AKAP17A ARL6IP4 C16orf87 C1orf35 CACNA1A CDC37 CLK1 CLK4 FAM9B LUC7L2 LUZP4 MCRS1 RBM25 RBM39 RBMX2 RNPS1 RSRC1 SNIP1 SNRNP70 SRRM1 SRSF11 TBC1D26 U2AF1 WDR5 ZNF124 ZNF286A ZNF699 ZRSR2 ZRSR2P1	53 interacting genes: AP1B1 AP2B1 CARNMT1 CHERP CIR1 CLK2 DHX38 EFHC2 EPB41 FRA10AC1 HINFP HMGB2 HNRNPK HNRNPM IL7R JMJD6 KRT1 KRT75 MAP1B MEOX2 MFAP1 MLH1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A PTEN RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRNP35 SNRPD1 SRPK1 SRRM4 SRSF1 SRSF2 SRSF3 SUV39H1 TOE1 TRA2B TRAPPC10 U2AF2 VEGFA ZCCHC10 ZNF417 ZRANB2 ZRSR2
Entrez ID		84530	7307
HPRD ID		13897	01871
Ensembl ID		ENSG00000139767	ENSG00000160201
Uniprot IDs		A7MD48 V5T9A0	P0DN76 Q01081 Q7Z780
PDB IDs			1JMT
Enriched GO Terms of Interacting Partners?
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