U2AF1 and PRPF4

Number of citations of the paper that reports this interaction (PubMedID 22365833)
163

Data Source:
BioGRID (two hybrid)

		U2AF1	PRPF4
Description		U2 small nuclear RNA auxiliary factor 1	pre-mRNA processing factor 4
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GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF Complex	Nucleus Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP U2-type Precatalytic Spliceosome Spliceosomal SnRNP Complex
	Molecular Function	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding	Protein Binding U6 SnRNA Binding U4 SnRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Blood and toenail selenium levels ( 25343990)	White matter growth ( 29682794)
Interacting Genes		53 interacting genes: AP1B1 AP2B1 CARNMT1 CHERP CIR1 CLK2 DHX38 EFHC2 EPB41 FRA10AC1 HINFP HMGB2 HNRNPK HNRNPM IL7R JMJD6 KRT1 KRT75 MAP1B MEOX2 MFAP1 MLH1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A PTEN RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRNP35 SNRPD1 SRPK1 SRRM4 SRSF1 SRSF2 SRSF3 SUV39H1 TOE1 TRA2B TRAPPC10 U2AF2 VEGFA ZCCHC10 ZNF417 ZRANB2 ZRSR2	9 interacting genes: APP ATP5MF CLK1 GPKOW PPIH SRSF1 TGFBR1 U2AF1 WBP4
Entrez ID		7307	9128
HPRD ID		01871	08479
Ensembl ID		ENSG00000160201	ENSG00000136875
Uniprot IDs		P0DN76 Q01081 Q7Z780	O43172 Q5T1M7
PDB IDs		1JMT	1MZW 3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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