WDR24 and SESN1

Number of citations of the paper that reports this interaction (PubMedID 25263562)
166

Data Source:
BioGRID (pull down)

		WDR24	SESN1
Description		WD repeat domain 24	sestrin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Cytosol Intracellular Membrane-bounded Organelle GATOR2 Complex	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Oxidoreductase Activity, Acting On Peroxide As Acceptor Peroxiredoxin Activity Leucine Binding
	Biological Process	Autophagy Regulation Of Autophagy Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation	Positive Regulation Of Macroautophagy Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Cellular Response To Leucine Reactive Oxygen Species Metabolic Process Cellular Oxidant Detoxification Regulation Of Response To Reactive Oxygen Species Negative Regulation Of TORC1 Signaling Cellular Response To Leucine Starvation
Pathways		Amino acids regulate mTORC1	Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Hip circumference adjusted for BMI ( 34021172) Smoking initiation (ever regular vs never regular) ( 30679032)	Asthma ( 32296059) Birth weight ( 31043758) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 27863252) Metabolite levels ( 23823483) Offspring birth weight ( 31043758) Prostate cancer ( 23535732)
Interacting Genes		5 interacting genes: APPBP2 FBXO7 SESN1 SESN3 SRPK2	3 interacting genes: MIOS PRDX1 WDR24
Entrez ID		84219	27244
HPRD ID		15665	07310
Ensembl ID		ENSG00000127580	ENSG00000080546
Uniprot IDs		Q96S15	Q9Y6P5
PDB IDs
Enriched GO Terms of Interacting Partners?
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