SESN1 and WDR24

Number of citations of the paper that reports this interaction (PubMedID 25263562)
166

Data Source:
BioGRID (pull down)

		SESN1	WDR24
Description		sestrin 1	WD repeat domain 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol	Lysosomal Membrane Cytosol Intracellular Membrane-bounded Organelle GATOR2 Complex
	Molecular Function	Protein Binding Oxidoreductase Activity, Acting On Peroxide As Acceptor Peroxiredoxin Activity Leucine Binding	Protein Binding
	Biological Process	Positive Regulation Of Macroautophagy Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Cellular Response To Leucine Reactive Oxygen Species Metabolic Process Cellular Oxidant Detoxification Regulation Of Response To Reactive Oxygen Species Negative Regulation Of TORC1 Signaling Cellular Response To Leucine Starvation	Autophagy Regulation Of Autophagy Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation
Pathways		Amino acids regulate mTORC1	Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Asthma ( 32296059) Birth weight ( 31043758) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 27863252) Metabolite levels ( 23823483) Offspring birth weight ( 31043758) Prostate cancer ( 23535732)	Age at first sexual intercourse ( 34211149) Hip circumference adjusted for BMI ( 34021172) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		3 interacting genes: MIOS PRDX1 WDR24	5 interacting genes: APPBP2 FBXO7 SESN1 SESN3 SRPK2
Entrez ID		27244	84219
HPRD ID		07310	15665
Ensembl ID		ENSG00000080546	ENSG00000127580
Uniprot IDs		Q9Y6P5	Q96S15
PDB IDs
Enriched GO Terms of Interacting Partners?
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