PIP5K1B and PIP5KL1

Number of citations of the paper that reports this interaction (PubMedID 14701839)
9

Data Source:
HPRD (in vivo)

		PIP5K1B	PIP5KL1
Description		phosphatidylinositol-4-phosphate 5-kinase type 1 beta	phosphatidylinositol-4-phosphate 5-kinase like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Uropod Cytosol Plasma Membrane Endomembrane System	Cytosol Membrane Cell Projection
	Molecular Function	1-phosphatidylinositol-3-phosphate 5-kinase Activity Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-kinase Activity Phosphatidylinositol-3,4-bisphosphate 5-kinase Activity	ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity
	Biological Process	Phosphatidylinositol Biosynthetic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Phosphorylation Phosphatidylinositol Phosphate Biosynthetic Process	Negative Regulation Of Protein Phosphorylation Negative Regulation Of Mitochondrial Membrane Potential Phosphorylation Negative Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Phosphatidylinositol Phosphate Biosynthetic Process
Pathways		Synthesis of PIPs at the plasma membrane WNT mediated activation of DVL PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Body mass index (recreational physical activity interaction) ( 23192594) Chronic kidney disease ( 31152163 20383146) Creatinine levels ( 31015462) Estimated glomerular filtration rate ( 31152163 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 27588450) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Systolic blood pressure ( 30578418)	Body mass index ( 26426971)
Interacting Genes		2 interacting genes: BTK PIP5KL1	2 interacting genes: PIP5K1A PIP5K1B
Entrez ID		8395	138429
HPRD ID		04121	15139
Ensembl ID		ENSG00000107242	ENSG00000167103
Uniprot IDs		O14986 Q7KYT6	Q5T9C9
PDB IDs
Enriched GO Terms of Interacting Partners?
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