PIP5KL1 and PIP5K1B

Number of citations of the paper that reports this interaction (PubMedID 14701839)
9

Data Source:
HPRD (in vivo)

		PIP5KL1	PIP5K1B
Description		phosphatidylinositol-4-phosphate 5-kinase like 1	phosphatidylinositol-4-phosphate 5-kinase type 1 beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane Cell Projection	Uropod Cytosol Plasma Membrane Endomembrane System
	Molecular Function	ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity	1-phosphatidylinositol-3-phosphate 5-kinase Activity Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-kinase Activity Phosphatidylinositol-3,4-bisphosphate 5-kinase Activity
	Biological Process	Negative Regulation Of Protein Phosphorylation Negative Regulation Of Mitochondrial Membrane Potential Phosphorylation Negative Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Phosphatidylinositol Phosphate Biosynthetic Process	Phosphatidylinositol Biosynthetic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Phosphorylation Phosphatidylinositol Phosphate Biosynthetic Process
Pathways			Synthesis of PIPs at the plasma membrane WNT mediated activation of DVL PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Body mass index (recreational physical activity interaction) ( 23192594) Chronic kidney disease ( 31152163 20383146) Creatinine levels ( 31015462) Estimated glomerular filtration rate ( 31152163 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 27588450) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Systolic blood pressure ( 30578418)
Interacting Genes		2 interacting genes: PIP5K1A PIP5K1B	2 interacting genes: BTK PIP5KL1
Entrez ID		138429	8395
HPRD ID		15139	04121
Ensembl ID		ENSG00000167103	ENSG00000107242
Uniprot IDs		Q5T9C9	O14986 Q7KYT6
PDB IDs
Enriched GO Terms of Interacting Partners?
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