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YPEL3 and HGS
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
86
Data Source:
BioGRID
(two hybrid)
YPEL3
HGS
Description
yippee like 3
hepatocyte growth factor-regulated tyrosine kinase substrate
Image
No pdb structure
GO Annotations
Cellular Component
Nucleolus
Lysosome
Endosome
Early Endosome
Cytosol
Early Endosome Membrane
Multivesicular Body Membrane
ESCRT-0 Complex
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Phagocytic Vesicle Lumen
Molecular Function
Metal Ion Binding
Protein Binding
Protein Domain Specific Binding
Phosphatidylinositol Binding
Ubiquitin Binding
Ubiquitin-like Protein Ligase Binding
Metal Ion Binding
Biological Process
Positive Regulation Of Cellular Senescence
Protein Targeting To Lysosome
Signal Transduction
Negative Regulation Of Cell Population Proliferation
Membrane Invagination
Positive Regulation Of Gene Expression
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Endosomal Transport
Macroautophagy
Negative Regulation Of Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Multivesicular Body Assembly
Regulation Of Protein Catabolic Process
Regulation Of MAP Kinase Activity
Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT
Protein Localization To Membrane
Positive Regulation Of Exosomal Secretion
Pathways
EGFR downregulation
Lysosome Vesicle Biogenesis
Ub-specific processing proteases
Negative regulation of MET activity
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
InlB-mediated entry of Listeria monocytogenes into host cell
RHOU GTPase cycle
Endosomal Sorting Complex Required For Transport (ESCRT)
Inhibition of membrane repair
Prevention of phagosomal-lysosomal fusion
RHOBTB3 ATPase cycle
Drugs
Citric acid
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Body fat distribution (arm fat ratio) (
30664634
)
Brain morphology (MOSTest) (
32665545
)
Schizophrenia (
28991256
25056061
29483656
)
Eye color traits (
20463881
)
Refractive error (
32231278
)
Interacting Genes
121 interacting genes:
APP
ARMC7
ATG9A
ATXN1L
BCAS2
C10orf55
C19orf54
C1orf109
CABP2
CDCA4
CDKN2D
COL8A1
CRYBA1
CRYBA2
CYB5R2
CYSRT1
DMRT3
DOK6
DOK7
EID2B
FAM168B
FANCL
FGF21
FHL2
FHL3
FHL5
FNDC3B
FRS3
GCA
GCM2
GEM
GUCD1
HDAC7
HEXIM2
HGS
HNRNPH1
HOXA1
HR
HSD3B7
HSPB2
HSPB2-C11orf52
INTS11
KLHL38
KRTAP13-2
KRTAP15-1
KRTAP23-1
KRTAP3-1
KRTAP3-3
KRTAP6-2
LARP4
LIMS3
LIMS4
LMO2
LONRF1
MAD2L2
MDFI
MKRN3
MORN3
MYOZ1
MYOZ3
NRF1
NUFIP2
ODAM
OSTF1
OTX1
PIK3R3
PITX1
PLSCR4
POLD1
POLR1C
POU2AF1
PPP2CA
PRKAA2
PRKAB2
PRR13
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMA3
QRICH1
RBPMS
RFC5
SH2D4A
SHC3
SMUG1
SPAG8
SPG21
SPRYD7
SRPK2
STK16
TASOR2
TBX6
TENT5A
TENT5B
TEPSIN
TGM7
TLE5
TLX3
TOX2
TP53INP1
TRAPPC2L
TRAPPC6A
TRIM10
TRIM55
TRIM63
TRIM73
TRIP6
TSC1
TSSK3
UBTD2
VENTX
VGLL3
VWC2L
WWOX
ZIC1
ZNF441
ZNF76
ZNF765
ZYX
328 interacting genes:
ABI2
ACLY
ACOT11
ACTN3
ADRA2C
AHCYL1
AKAP8L
ANKRD55
ANTKMT
APC
APLP2
APP
ARFIP2
ARL6IP1
ARMC7
ASB12
ATN1
ATP1A1
ATP2A2
ATXN1L
BBC3
BCAS2
BEGAIN
BFSP2
BICRAL
BLOC1S1
BORCS6
BRINP3
BSG
C11orf1
C1orf94
C20orf173
C3orf36
C9orf24
CASK
CBS
CCDC103
CCDC136
CCDC196
CCDC33
CCND3
CDR2
CDSN
CEACAM6
CEP55
CEP57L1
CEP63
CEP68
CLTC
COG8
CRMP1
CRX
CSNK2A1
CSTF2
CSTF2T
CTTNBP2NL
CYB5R2
DAAM2
DAZAP2
DCTN2
DECR1
DEUP1
DGCR6
DLG4
DSN1
DTX2
DYDC1
EFHC2
EGFL7
EGFR
EHMT2
EIF3F
EPS15
ESRRG
EXOC3L1
EXOC5
EXOC7
EXOC8
EYA2
FAM166A
FAM168A
FAM185A
FANCG
FBN1
FCHSD2
FIGN
FLOT1
FLOT2
FNDC11
FOXD4L1
FOXI1
FSD2
FTCD
GATC
GFAP
GFI1B
GGA2
GKAP1
GOLGA2
GOLGA6L9
GOLGA7B
GUCA1C
HAP1
HAUS1
HNRNPDL
HNRNPM
HSF4
HSFY1
HSPA8
ICA1L
IFNA16
IFT74
IL2RB
IL4R
ILKAP
ING5
INTS4
IPO4
JAKMIP2
JMJD7
KIAA0753
KIAA0825
KLF4
KRT13
KRT14
KRT15
KRT16
KRT18
KRT19
KRT24
KRT25
KRT26
KRT27
KRT3
KRT31
KRT33B
KRT34
KRT35
KRT36
KRT37
KRT38
KRT39
KRT40
KRT6A
KRT75
KRT76
KRT82
KRT86
KRTAP19-5
KRTAP26-1
KRTAP7-1
LASP1
LDOC1
LINC00265
LITAF
LMO1
LMO4
LRRC61
LURAP1
LYST
MAGEB4
MAGED1
MAP3K1
MAP3K10
MAP3K7
MAPK1IP1L
MARK4
MAT2A
MED21
MED22
MED25
MED30
MED4
MED7
MEIS3
MEST
MET
METTL27
MIF4GD
MKNK1
MKRN3
MRFAP1L1
MTHFD1L
NADSYN1
NDC80
NDUFB10
NEDD4
NEDD8
NEFL
NF2
NFYC
NMI
NPAS2
NUP54
NUP62
NUTM2F
ODAD1
ODAM
OIP5
OSBPL5
P4HA3
PAK1
PAX5
PAX6
PEF1
PELP1
PFKM
PIK3R1
PITX1
PKNOX2
PLA2G10
PLAAT1
PLCD1
PLD3
PLEKHB2
PMEPA1
PNMA1
POGZ
POU2AF1
POU6F2
PPP1R16A
PPP1R32
PPP1R7
PPP2R3B
PRR22
PRR5
PSMB11
PSMB4
PTCD3
RASSF4
RBCK1
RFC2
RFX6
RHOBTB3
RINT1
RNF4
RPRD1A
RPS3A
RSPO4
RSU1
RUNX1
SAPCD1
SCAMP3
SCRN1
SCT
SDS
SERGEF
SERTAD3
SF3B3
SHANK3
SMAD2
SMAD3
SMAD5
SMARCB1
SNAP25
SNX1
SNX5
SNX7
SORBS3
SPATA12
SPC25
SPIRE2
SS18L1
STAM
STAM2
STK32C
STMN3
STX11
STXBP1
SUMO1
SUN2
SYK
TADA2A
TASOR2
TBX19
TCP11L2
TEKT1
TEKT5
TFG
TIMM10B
TIMMDC1
TJP2
TLE5
TMCC2
TOM1L1
TP53BP1
TRAF1
TRAF4
TRAK1
TRAP1
TRIM10
TRIM17
TRIM23
TRIM27
TRIM54
TRIM69
TRIM73
TRIML2
TSC1
TSG101
TUBB
TUBB2A
UBA1
UBA52
UBAP2
UBB
UBC
UBE2I
UBE4B
UBQLN1
UBQLN4
UBQLNL
UBXN11
USHBP1
USP54
VGLL3
VMP1
VPS37A
VPS37B
VPS37C
VPS37D
VPS52
WASHC1
YPEL3
ZNF302
ZNF34
ZNF430
ZNF44
Entrez ID
83719
9146
HPRD ID
15683
05085
Ensembl ID
ENSG00000090238
ENSG00000185359
Uniprot IDs
A0A024R624
P61236
A0A0S2Z4R4
O14964
PDB IDs
2D3G
3F1I
3OBQ
3ZYQ
4AVX
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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