YPEL3 and CRYBA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		YPEL3	CRYBA1
Description		yippee like 3	crystallin beta A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus	Nucleus Cytoplasm
	Molecular Function	Metal Ion Binding	Molecular_function Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Positive Regulation Of Cellular Senescence	Negative Regulation Of Cytokine Production Lens Development In Camera-type Eye Visual Perception Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Anoikis
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Schizophrenia ( 28991256 25056061 29483656)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mean reticulocyte volume ( 32888494) Night sleep phenotypes ( 27126917)
Interacting Genes		121 interacting genes: APP ARMC7 ATG9A ATXN1L BCAS2 C10orf55 C19orf54 C1orf109 CABP2 CDCA4 CDKN2D COL8A1 CRYBA1 CRYBA2 CYB5R2 CYSRT1 DMRT3 DOK6 DOK7 EID2B FAM168B FANCL FGF21 FHL2 FHL3 FHL5 FNDC3B FRS3 GCA GCM2 GEM GUCD1 HDAC7 HEXIM2 HGS HNRNPH1 HOXA1 HR HSD3B7 HSPB2 HSPB2-C11orf52 INTS11 KLHL38 KRTAP13-2 KRTAP15-1 KRTAP23-1 KRTAP3-1 KRTAP3-3 KRTAP6-2 LARP4 LIMS3 LIMS4 LMO2 LONRF1 MAD2L2 MDFI MKRN3 MORN3 MYOZ1 MYOZ3 NRF1 NUFIP2 ODAM OSTF1 OTX1 PIK3R3 PITX1 PLSCR4 POLD1 POLR1C POU2AF1 PPP2CA PRKAA2 PRKAB2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 QRICH1 RBPMS RFC5 SH2D4A SHC3 SMUG1 SPAG8 SPG21 SPRYD7 SRPK2 STK16 TASOR2 TBX6 TENT5A TENT5B TEPSIN TGM7 TLE5 TLX3 TOX2 TP53INP1 TRAPPC2L TRAPPC6A TRIM10 TRIM55 TRIM63 TRIM73 TRIP6 TSC1 TSSK3 UBTD2 VENTX VGLL3 VWC2L WWOX ZIC1 ZNF441 ZNF76 ZNF765 ZYX	33 interacting genes: ARID5A BANF2 CELF6 CERK CHCHD2 CPD CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 CYSRT1 EVI2A EVI2B FBXO3 FOXH1 HOXC8 KLK10 KRTAP11-1 KRTAP13-2 KRTAP13-3 LASP1 NF1 NOXA1 OMG PLEKHF2 PROP1 RBPMS RHOXF2 SPRR1B TAF15 VAC14 YPEL3
Entrez ID		83719	1411
HPRD ID		15683	00429
Ensembl ID		ENSG00000090238	ENSG00000108255
Uniprot IDs		A0A024R624 P61236	P05813
PDB IDs
Enriched GO Terms of Interacting Partners?
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