FZD9 and WNT2

Number of citations of the paper that reports this interaction (PubMedID 12138115)
37

Data Source:
HPRD (in vivo)

		FZD9	WNT2
Description		frizzled class receptor 9	Wnt family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Cell Surface Integral Component Of Membrane Filopodium Membrane Mitochondrial Membrane Perinuclear Region Of Cytoplasm Postsynapse Glutamatergic Synapse	Extracellular Region Extracellular Space Cytoplasm Extrinsic Component Of External Side Of Plasma Membrane Collagen-containing Extracellular Matrix Wnt Signalosome
	Molecular Function	G Protein-coupled Receptor Activity Wnt-protein Binding Protein Homodimerization Activity Wnt-activated Receptor Activity Protein Heterodimerization Activity	Frizzled Binding Cytokine Activity Protein Binding Receptor Ligand Activity
	Biological Process	Ossification Release Of Cytochrome C From Mitochondria G Protein-coupled Receptor Signaling Pathway Nervous System Development Neuroblast Proliferation Learning Or Memory B Cell Differentiation Positive Regulation Of Bone Mineralization Non-canonical Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Cell Cycle Negative Regulation Of Mitochondrial Depolarization Canonical Wnt Signaling Pathway Negative Regulation Of Necroptotic Process Positive Regulation Of Canonical Wnt Signaling Pathway Postsynapse Organization Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Negative Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Bone Regeneration Positive Regulation Of Neural Precursor Cell Proliferation	Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Mesenchymal Cell Proliferation Lens Development In Camera-type Eye Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Neurogenesis Neuron Differentiation Lung Development Cell Proliferation In Midbrain Cell Fate Commitment Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of DNA-binding Transcription Factor Activity Atrial Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Cardiac Muscle Cell Proliferation Canonical Wnt Signaling Pathway Cardiac Epithelial To Mesenchymal Transition Lung Induction Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Labyrinthine Layer Blood Vessel Development Iris Morphogenesis Mammary Gland Epithelium Development Cellular Response To Retinoic Acid Cellular Response To Transforming Growth Factor Beta Stimulus Midbrain Dopaminergic Neuron Differentiation Canonical Wnt Signaling Pathway Involved In Midbrain Dopaminergic Neuron Differentiation
Pathways		Class B/2 (Secretin family receptors)	WNT ligand biogenesis and trafficking WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Lamb consumption ( 32066663) Malaria ( 31844061) Meat-related diet ( 32066663) Non-oily fish consumption ( 32066663) Protein C levels ( 28082259)	Dupuytren's disease ( 28886342 21732829) Inflammatory bowel disease ( 28067908) Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573) Tonsillectomy ( 27182965 28928442) Ulcerative colitis ( 28067908) Uterine fibroids ( 31649266) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		6 interacting genes: KRTAP10-3 MDFI SIAH1 WNT1 WNT2 WNT7A	8 interacting genes: AQP5 FZD1 FZD9 HCK RRAGC SFRP1 UQCR11 WNT3A
Entrez ID		8326	7472
HPRD ID		03460	00999
Ensembl ID		ENSG00000188763	ENSG00000105989
Uniprot IDs		O00144	A0A384MDX3 P09544
PDB IDs
Enriched GO Terms of Interacting Partners?
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