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WNT2
Description
Wnt family member 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Extrinsic Component Of External Side Of Plasma Membrane
Collagen-containing Extracellular Matrix
Wnt Signalosome
Molecular Function
Frizzled Binding
Cytokine Activity
Protein Binding
Receptor Ligand Activity
Biological Process
Positive Regulation Of Endothelial Cell Proliferation
Positive Regulation Of Mesenchymal Cell Proliferation
Lens Development In Camera-type Eye
Cell-cell Signaling
Positive Regulation Of Cell Population Proliferation
Neurogenesis
Neuron Differentiation
Lung Development
Cell Proliferation In Midbrain
Cell Fate Commitment
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Fibroblast Proliferation
Positive Regulation Of Neurogenesis
Positive Regulation Of DNA-binding Transcription Factor Activity
Atrial Cardiac Muscle Tissue Morphogenesis
Positive Regulation Of Cardiac Muscle Cell Proliferation
Canonical Wnt Signaling Pathway
Cardiac Epithelial To Mesenchymal Transition
Lung Induction
Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Labyrinthine Layer Blood Vessel Development
Iris Morphogenesis
Mammary Gland Epithelium Development
Cellular Response To Retinoic Acid
Cellular Response To Transforming Growth Factor Beta Stimulus
Midbrain Dopaminergic Neuron Differentiation
Canonical Wnt Signaling Pathway Involved In Midbrain Dopaminergic Neuron Differentiation
Pathways
WNT ligand biogenesis and trafficking
WNT ligand biogenesis and trafficking
Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS
Dupuytren's disease (
28886342
21732829
)
Inflammatory bowel disease (
28067908
)
Response to platinum-based chemotherapy in non-small-cell lung cancer (
22872573
)
Tonsillectomy (
27182965
28928442
)
Ulcerative colitis (
28067908
)
Uterine fibroids (
31649266
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
8 interacting genes:
AQP5
FZD1
FZD9
HCK
RRAGC
SFRP1
UQCR11
WNT3A
Entrez ID
7472
HPRD ID
00999
Ensembl ID
ENSG00000105989
Uniprot IDs
A0A384MDX3
P09544
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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