WNT2 and UQCR11

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		WNT2	UQCR11
Description		Wnt family member 2	ubiquinol-cytochrome c reductase, complex III subunit XI
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Extrinsic Component Of External Side Of Plasma Membrane Collagen-containing Extracellular Matrix Wnt Signalosome	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III
	Molecular Function	Frizzled Binding Cytokine Activity Protein Binding Receptor Ligand Activity	Electron Transfer Activity
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Mesenchymal Cell Proliferation Lens Development In Camera-type Eye Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Neurogenesis Neuron Differentiation Lung Development Cell Proliferation In Midbrain Cell Fate Commitment Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of DNA-binding Transcription Factor Activity Atrial Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Cardiac Muscle Cell Proliferation Canonical Wnt Signaling Pathway Cardiac Epithelial To Mesenchymal Transition Lung Induction Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Labyrinthine Layer Blood Vessel Development Iris Morphogenesis Mammary Gland Epithelium Development Cellular Response To Retinoic Acid Cellular Response To Transforming Growth Factor Beta Stimulus Midbrain Dopaminergic Neuron Differentiation Canonical Wnt Signaling Pathway Involved In Midbrain Dopaminergic Neuron Differentiation	Generation Of Precursor Metabolites And Energy Mitochondrial Electron Transport, Ubiquinol To Cytochrome C
Pathways		WNT ligand biogenesis and trafficking WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors)	Respiratory electron transport
Drugs			6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases
GWAS		Dupuytren's disease ( 28886342 21732829) Inflammatory bowel disease ( 28067908) Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573) Tonsillectomy ( 27182965 28928442) Ulcerative colitis ( 28067908) Uterine fibroids ( 31649266) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		8 interacting genes: AQP5 FZD1 FZD9 HCK RRAGC SFRP1 UQCR11 WNT3A	2 interacting genes: TUBB4A WNT2
Entrez ID		7472	10975
HPRD ID		00999	15628
Ensembl ID		ENSG00000105989	ENSG00000127540
Uniprot IDs		A0A384MDX3 P09544	O14957
PDB IDs			5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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