VMP1 and CYB5R3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		VMP1	CYB5R3
Description		vacuole membrane protein 1	cytochrome b5 reductase 3
Image		No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Autophagosome Membrane Nucleolus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Endomembrane System Membrane Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex
	Molecular Function	Protein Binding	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding
	Biological Process	Autophagosome Assembly Autophagy Golgi Organization Embryo Implantation Autophagosome Membrane Docking Cell Junction Assembly Lipoprotein Transport Cell-cell Adhesion Organelle Localization By Membrane Tethering Positive Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Mitochondrion-endoplasmic Reticulum Membrane Tethering	Cholesterol Biosynthetic Process Nitric Oxide Biosynthetic Process Blood Circulation
Pathways			Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs			NADH Flavin adenine dinucleotide Copper
Diseases
GWAS		Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Hematocrit ( 32888494 27863252) Hemoglobin ( 29403010 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Idiopathic dilated cardiomyopathy ( 29495422) Lymphocyte counts ( 27863252) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244 24076602) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Pulse pressure ( 27841878) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Triglyceride levels ( 32203549 32154731) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) White blood cell count ( 32888494 27863252) White blood cell count (basophil) ( 27863252)	Initial pursuit acceleration ( 29064472)
Interacting Genes		9 interacting genes: CYB5R3 ERGIC3 FAM209A HGS LMNA MEOX2 SLC39A9 TMEM41B TRPC4AP	68 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ARSA ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAS1 GAST GPR152 GRM2 HBG2 HSD17B13 L3MBTL2 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 RPS6KB1 SBF1 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C TUBGCP6 UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 XPNPEP3 ZDHHC15
Entrez ID		81671	1727
HPRD ID		15649	08942
Ensembl ID		ENSG00000062716	ENSG00000100243
Uniprot IDs		B4DED7 B4DEJ9 B4DGZ7 D3DU01 Q96GC9	P00387
PDB IDs			1M91 1UMK
Enriched GO Terms of Interacting Partners?
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