CYB5R3 and MFSD6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYB5R3	MFSD6
Description		cytochrome b5 reductase 3	major facilitator superfamily domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding	Protein Binding
	Biological Process	Cholesterol Biosynthetic Process Nitric Oxide Biosynthetic Process Blood Circulation	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Pathways		Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs		NADH Flavin adenine dinucleotide Copper
Diseases
GWAS		Initial pursuit acceleration ( 29064472)	Arthritis (juvenile idiopathic) ( 33106285) Daytime sleep phenotypes ( 27126917) Estimated glomerular filtration rate ( 31015462) Medication use (thyroid preparations) ( 31015401) Platelet count ( 32888494)
Interacting Genes		68 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ARSA ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAS1 GAST GPR152 GRM2 HBG2 HSD17B13 L3MBTL2 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 RPS6KB1 SBF1 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C TUBGCP6 UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 XPNPEP3 ZDHHC15	43 interacting genes: ADIPOQ ALG8 ANKAR APH1A APOL3 AQP7 C19orf18 C2orf88 CD79A CYB5R3 EBP ERGIC3 GJA8 GJB2 GPR152 GPR42 GPX8 HIBCH LY6E MFSD4B MSTN NKG7 OSGEPL1 PDCD1LG2 SELENOK SGPL1 SHISAL1 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC39A2 SMIM1 SSMEM1 STAT1 STX12 SYNDIG1 TMEM179B TMEM237 TMEM242 TMEM258 TSPO2 WDR75
Entrez ID		1727	54842
HPRD ID		08942	13369
Ensembl ID		ENSG00000100243	ENSG00000151690
Uniprot IDs		P00387	Q6ZSS7
PDB IDs		1M91 1UMK
Enriched GO Terms of Interacting Partners?
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