HSD3B7 and FBLN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HSD3B7	FBLN2
Description		hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	fibulin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Lipid Droplet Integral Component Of Membrane	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Vesicle
	Molecular Function	3-beta-hydroxy-delta5-steroid Dehydrogenase Activity Protein Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase Activity	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding
	Biological Process	Bile Acid Biosynthetic Process B Cell Chemotaxis	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways		Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol Synthesis of bile acids and bile salts via 27-hydroxycholesterol	Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases
GWAS			Bipolar disorder with mood-incongruent psychosis ( 23092984) Body mass index ( 26426971) Hip circumference adjusted for BMI ( 34021172) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes		56 interacting genes: ADAMTSL4 AGR2 ANAPC11 APPBP2 ARID5A ASB12 BTN2A2 C22orf39 COMT CREB5 CYSRT1 DAPP1 EFEMP1 EFEMP2 EGFL7 ELOVL4 EMG1 FBLN2 GLRX3 HOXA1 HSD17B13 ICAM1 KPNA4 KPRP KRT31 KRT40 KRT86 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP13-3 KRTAP19-2 KRTAP4-2 KRTAP5-9 LCE4A LINGO1 MEI4 MEOX2 MGAT5B NOTCH2NLA NR4A3 OTX2 PYGL RBP3 REEP4 RGS17 SPRY2 SSC4D TMEM31 TRIM42 YPEL3 ZBTB42 ZNF655	33 interacting genes: ACAN ATN1 BCAN COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL8A1 ELN ERCC6 FBN1 FBXW5 FN1 HOXA1 HSD3B7 HSPG2 ITGB3 JOSD1 LAMA1 LAMA5 LAMC2 LCE3D MRPS25 NID1 NUFIP2 OTX1 PRELP VCAN ZNF408 ZNF414
Entrez ID		80270	2199
HPRD ID		09680	00630
Ensembl ID		ENSG00000099377	ENSG00000163520
Uniprot IDs		Q9H2F3	P98095 Q86V58 Q9Y3V7
PDB IDs
Enriched GO Terms of Interacting Partners?
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