HSD3B7 and EMG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HSD3B7	EMG1
Description		hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	EMG1 N1-specific pseudouridine methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Lipid Droplet Integral Component Of Membrane	Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Small-subunit Processome
	Molecular Function	3-beta-hydroxy-delta5-steroid Dehydrogenase Activity Protein Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase Activity	RNA Binding Protein Binding RRNA Binding Identical Protein Binding RRNA (pseudouridine) Methyltransferase Activity
	Biological Process	Bile Acid Biosynthetic Process B Cell Chemotaxis	Blastocyst Development RRNA Processing Nucleologenesis Ribosomal Small Subunit Biogenesis RRNA Base Methylation
Pathways		Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol Synthesis of bile acids and bile salts via 27-hydroxycholesterol	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS
Interacting Genes		56 interacting genes: ADAMTSL4 AGR2 ANAPC11 APPBP2 ARID5A ASB12 BTN2A2 C22orf39 COMT CREB5 CYSRT1 DAPP1 EFEMP1 EFEMP2 EGFL7 ELOVL4 EMG1 FBLN2 GLRX3 HOXA1 HSD17B13 ICAM1 KPNA4 KPRP KRT31 KRT40 KRT86 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP13-3 KRTAP19-2 KRTAP4-2 KRTAP5-9 LCE4A LINGO1 MEI4 MEOX2 MGAT5B NOTCH2NLA NR4A3 OTX2 PYGL RBP3 REEP4 RGS17 SPRY2 SSC4D TMEM31 TRIM42 YPEL3 ZBTB42 ZNF655	15 interacting genes: ANXA3 APP CTSE FAM74A4 HIVEP1 HSD3B7 IL7R KHDRBS1 MCPH1 NAA80 PSMB7 PSME1 SLC25A38 SUMO2 ZNF768
Entrez ID		80270	10436
HPRD ID		09680	12803
Ensembl ID		ENSG00000099377	ENSG00000126749
Uniprot IDs		Q9H2F3	Q92979
PDB IDs			5FAI
Enriched GO Terms of Interacting Partners?
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