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HSD3B7

Description hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum Membrane
  • Lipid Droplet
  • Integral Component Of Membrane
Molecular Function
  • 3-beta-hydroxy-delta5-steroid Dehydrogenase Activity
  • Protein Binding
  • Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
  • Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase Activity
Biological Process
  • Bile Acid Biosynthetic Process
  • B Cell Chemotaxis
Pathways
  • Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
  • Synthesis of bile acids and bile salts via 24-hydroxycholesterol
  • Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Drugs
Diseases
GWAS
Interacting Genes 56 interacting genes: ADAMTSL4 AGR2 ANAPC11 APPBP2 ARID5A ASB12 BTN2A2 C22orf39 COMT CREB5 CYSRT1 DAPP1 EFEMP1 EFEMP2 EGFL7 ELOVL4 EMG1 FBLN2 GLRX3 HOXA1 HSD17B13 ICAM1 KPNA4 KPRP KRT31 KRT40 KRT86 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP13-3 KRTAP19-2 KRTAP4-2 KRTAP5-9 LCE4A LINGO1 MEI4 MEOX2 MGAT5B NOTCH2NLA NR4A3 OTX2 PYGL RBP3 REEP4 RGS17 SPRY2 SSC4D TMEM31 TRIM42 YPEL3 ZBTB42 ZNF655
Entrez ID 80270
HPRD ID 09680
Ensembl ID ENSG00000099377
Uniprot IDs Q9H2F3
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025