EFHC2 and AASDHPPT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EFHC2	AASDHPPT
Description		EF-hand domain containing 2	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
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GO Annotations	Cellular Component	Microtubule Axoneme Ciliary Basal Body Mitotic Spindle	Cytosol Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Alpha-tubulin Binding	Magnesium Ion Binding Protein Binding Holo-[acyl-carrier-protein] Synthase Activity
	Biological Process	Mitotic Cytokinesis Mitotic Spindle Organization Regulation Of Neuron Projection Development Cilium-dependent Cell Motility Cellular Response To Leukemia Inhibitory Factor	Pantothenate Metabolic Process Protein Phosphopantetheinylation Lysine Biosynthetic Process Via Aminoadipic Acid
Pathways			Vitamin B5 (pantothenate) metabolism
Drugs
Diseases
GWAS		Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483) Glaucoma (primary open-angle) ( 33627673) Mean arterial pressure ( 29403010)	Coronary artery disease in type 1 diabetes ( 32077919) Upper eyelid morphology ( 29921221)
Interacting Genes		100 interacting genes: - AASDHPPT ARHGEF5 ARMC7 CABP2 CACNB4 CARD9 CCDC102B CCDC120 CCDC13 CCDC57 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CPNE2 CPNE7 CYFIP1 DCLK1 DDX6 DGCR6 DRC7 EDC3 EFHC1 EGLN3 EMD ENKD1 ESRRG EXOC8 EXOSC5 FAM107A FAM124B FAM214B FAM221B FBXL19 GEM GLYCTK GOLGA1 GPKOW GRB2 GYS1 HDAC4 HGS HNRNPLL INPP5J JAKMIP2 KANK2 KCTD7 KIF9 L3MBTL2 LMNB2 LMO2 LNX1 LONRF1 MAGOHB MAPK9 MID2 MISP MYLIP MYO5B NCDN NCK2 NDOR1 NEK6 NFKBID NME7 NR3C1 PBLD PHF1 PIBF1 PICK1 PLOD3 POLR1C PRPF18 PTK6 QARS1 RAD51D RCOR3 RECK RHOBTB3 RUNX1T1 SNRNP25 SOGA1 SPATA18 SPG21 STK16 TBC1D1 TBC1D22B TEKT4 TRIM42 TRIM50 TSSK3 TUBGCP4 TXK U2AF1 USP2 ZBTB16 ZFHX3 ZZZ3	6 interacting genes: CRX EFHC2 MDFI SIAH1 TRAF2 USP22
Entrez ID		80258	60496
HPRD ID		06540	09675
Ensembl ID		ENSG00000183690	ENSG00000149313
Uniprot IDs		Q5JST6	Q9NRN7
PDB IDs		2Z13 2Z14	2BYD 2C43 2CG5
Enriched GO Terms of Interacting Partners?
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