AASDHPPT and USP22

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		AASDHPPT	USP22
Description		aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	ubiquitin specific peptidase 22
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	SAGA Complex Nucleoplasm
	Molecular Function	Magnesium Ion Binding Protein Binding Holo-[acyl-carrier-protein] Synthase Activity	Transcription Coactivator Activity Thiol-dependent Deubiquitinase Protein Binding Zinc Ion Binding H4 Histone Acetyltransferase Activity Enzyme Binding Nuclear Receptor Coactivator Activity
	Biological Process	Pantothenate Metabolic Process Protein Phosphopantetheinylation Lysine Biosynthetic Process Via Aminoadipic Acid	Ubiquitin-dependent Protein Catabolic Process Cell Cycle Embryo Development Ending In Birth Or Egg Hatching Histone Ubiquitination Histone Deubiquitination Protein Deubiquitination Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle
Pathways		Vitamin B5 (pantothenate) metabolism	HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases
GWAS		Coronary artery disease in type 1 diabetes ( 32077919) Upper eyelid morphology ( 29921221)	Body mass index ( 26426971) Mosquito bite size ( 28199695)
Interacting Genes		6 interacting genes: CRX EFHC2 MDFI SIAH1 TRAF2 USP22	17 interacting genes: AASDHPPT ATXN7 ATXN7L3 B9D1 BAG4 H2AC20 H2BC21 HEXA MRPL10 MRPL44 MTUS2 PSME1 PTGS2 RCAN1 SCFD1 SIRT1 UBC
Entrez ID		60496	23326
HPRD ID		09675	19411
Ensembl ID		ENSG00000149313	ENSG00000124422
Uniprot IDs		Q9NRN7	Q9UPT9
PDB IDs		2BYD 2C43 2CG5
Enriched GO Terms of Interacting Partners?
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