NAA50 and NPHP3

		NAA50	NPHP3
Description		N-alpha-acetyltransferase 50, NatE catalytic subunit	nephrocystin 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol NatA Complex Extracellular Exosome	Extracellular Region Cytosol Cilium
	Molecular Function	Peptide Alpha-N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity H4 Histone Acetyltransferase Activity Peptidyl-lysine Acetyltransferase Activity	Protein Binding
	Biological Process	N-terminal Protein Amino Acid Acetylation Mitotic Sister Chromatid Cohesion Histone Acetylation Establishment Of Mitotic Sister Chromatid Cohesion Histone H4 Acetylation Mitotic Sister Chromatid Cohesion, Centromeric	Kidney Development Heart Looping Atrial Septum Development Determination Of Left/right Symmetry Wnt Signaling Pathway Lung Development Determination Of Pancreatic Left/right Asymmetry Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Convergent Extension Involved In Gastrulation Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Kidney Morphogenesis Determination Of Intestine Left/right Asymmetry Determination Of Stomach Left/right Asymmetry Determination Of Liver Left/right Asymmetry Ureter Development Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure
Pathways			Trafficking of myristoylated proteins to the cilium
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Diseases
GWAS		Prostate cancer ( 23535732)	Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Menarche (age at onset) ( 27182965 21102462) Serum alkaline phosphatase levels ( 33547301) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: BHLHE40 JMJD6 NAA10 NAA15 NPHP3 OTX2	18 interacting genes: ANAPC13 ASTE1 ATXN1 CCDC50 CDV3 COL7A1 DDX3Y DNAJC13 DPP7 DYSF EPC1 NAA50 NPHP1 PARP14 PIK3R4 PPP2R3A RAB6B TOPBP1
Entrez ID		80218	27031
HPRD ID		14350	06417
Ensembl ID		ENSG00000121579	ENSG00000113971
Uniprot IDs		E7EQ69 Q9GZZ1	Q7Z494
PDB IDs		2OB0 2PSW 3TFY 4X5K 6PPL 6PW9 6WF3 6WF5 6WFG 6WFK 6WFN 6WFO	5L7K
Enriched GO Terms of Interacting Partners?
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