NPHP3 and PPP2R3A

		NPHP3	PPP2R3A
Description		nephrocystin 3	protein phosphatase 2 regulatory subunit B''alpha
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GO Annotations	Cellular Component	Extracellular Region Cytosol Cilium	Protein Phosphatase Type 2A Complex
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Protein Phosphatase Regulator Activity
	Biological Process	Kidney Development Heart Looping Atrial Septum Development Determination Of Left/right Symmetry Wnt Signaling Pathway Lung Development Determination Of Pancreatic Left/right Asymmetry Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Convergent Extension Involved In Gastrulation Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Kidney Morphogenesis Determination Of Intestine Left/right Asymmetry Determination Of Stomach Left/right Asymmetry Determination Of Liver Left/right Asymmetry Ureter Development Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure	Protein Dephosphorylation Regulation Of Catalytic Activity Somite Development
Pathways		Trafficking of myristoylated proteins to the cilium
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Menarche (age at onset) ( 27182965 21102462) Serum alkaline phosphatase levels ( 33547301) Subcortical volume (MOSTest) ( 32665545)	Anticoagulant levels ( 22216198) Atrial fibrillation ( 30061737) Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Feeling nervous ( 29500382) Feeling worry ( 29500382) Fibrinogen levels ( 28107422 26561523) General factor of neuroticism ( 30867560) High density lipoprotein cholesterol levels ( 31928498) Intraocular pressure ( 29617998) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Myocardial infarction ( 33532862) Neurofibrillary tangles ( 31497858) Neutrophil percentage of white cells ( 32888494) Schizophrenia ( 25056061 29483656) Small cell lung carcinoma ( 28604730) Systolic blood pressure ( 31928498) Triglyceride levels ( 31928498) Waist circumference ( 31928498) Waist circumference adjusted for body mass index ( 34021172 25673412) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		18 interacting genes: ANAPC13 ASTE1 ATXN1 CCDC50 CDV3 COL7A1 DDX3Y DNAJC13 DPP7 DYSF EPC1 NAA50 NPHP1 PARP14 PIK3R4 PPP2R3A RAB6B TOPBP1	9 interacting genes: AKAP9 ATR ATXN7L2 CDC6 HMGB1 NPHP3 PPP5C PTPA RBL1
Entrez ID		27031	5523
HPRD ID		06417	09225
Ensembl ID		ENSG00000113971	ENSG00000073711
Uniprot IDs		Q7Z494	Q06190
PDB IDs		5L7K	4I5J 4I5K
Enriched GO Terms of Interacting Partners?
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