ARL14 and UBE2G2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ARL14	UBE2G2
Description		ADP ribosylation factor like GTPase 14	ubiquitin conjugating enzyme E2 G2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Cytoplasmic Vesicle	Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways			Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Attention deficit hyperactivity disorder ( 32279069) Diastolic blood pressure ( 27841878) Malaria ( 31844061) Pulse pressure ( 27841878) Response to methotrexate in rheumatoid arthritis ( 24583629) Systolic blood pressure ( 27841878)	Alanine aminotransferase levels ( 33547301)
Interacting Genes		4 interacting genes: ARNT EXOC3L1 SMURF1 UBE2G2	41 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN PSMG1 RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRAPPC10 TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4
Entrez ID		80117	7327
HPRD ID		07998	04387
Ensembl ID		ENSG00000179674	ENSG00000184787
Uniprot IDs		Q8N4G2	P60604
PDB IDs			2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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