UBE2G2 and TRIM3

Number of citations of the paper that reports this interaction (PubMedID 19690564)
64

Data Source:
BioGRID (two hybrid)

		UBE2G2	TRIM3
Description		ubiquitin conjugating enzyme E2 G2	tripartite motif containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lipid Droplet Cytosol	Cytoplasm Early Endosome Golgi Apparatus Dendrite
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding Protein C-terminus Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Protein Polyubiquitination Nervous System Development Protein Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	Interferon gamma signaling
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301)	Malaria ( 31844061)
Interacting Genes		41 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN PSMG1 RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRAPPC10 TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4	34 interacting genes: ACTN4 ASL CDKN1A CEP70 CSNK1D CSNK1E DNMT1 FXR1 FXR2 KCTD7 KIF21B LNX1 LRRC8E MYO5A MYO5B ROPN1 TEAD1 TEAD2 TNFAIP3 TPTEP2-CSNK1E TRIM2 TRIM21 TSC1 UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2G2 UBE2I UBE2K UBE2U UBE2Z USP32
Entrez ID		7327	10612
HPRD ID		04387	05690
Ensembl ID		ENSG00000184787	ENSG00000110171
Uniprot IDs		P60604	B7Z5Y8 O75382
PDB IDs		2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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