UBE2G2 and PSMG1

		UBE2G2	PSMG1
Description		ubiquitin conjugating enzyme E2 G2	proteasome assembly chaperone 1
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lipid Droplet Cytosol	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Chaperone Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Identical Protein Binding Ubiquitin Conjugating Enzyme Activity	Protein Binding Molecular Adaptor Activity Proteasome Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway Cellular Response To Interferon-beta Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Cerebellar Granule Cell Precursor Proliferation Chaperone-mediated Protein Complex Assembly Proteasome Core Complex Assembly
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301)	Alanine aminotransferase levels ( 33547301) Ankylosing spondylitis ( 20062062) C-reactive protein levels ( 21300955) Daytime nap ( 33568662) Daytime sleep phenotypes ( 27126917) Eye morphology ( 29921221) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422 26561523) Finger osteoarthritis severity (hand Klsum) ( 33055079) Glaucoma (primary open-angle) ( 33627673) Height ( 31562340) Inflammatory bowel disease ( 18758464) Pediatric autoimmune diseases ( 26301688) Primary sclerosing cholangitis ( 23603763 27992413) Serum alkaline phosphatase levels ( 33547301) Takayasu arteritis ( 23830517) Triglyceride levels ( 32203549) Ulcerative colitis ( 20228799)
Interacting Genes		41 interacting genes: AMFR ARL14 AUP1 BIRC8 CBL CNNM3 CPOX CUL9 ECPAS FARP2 HBS1L KDM2A MDM2 MGRN1 MLLT6 MUL1 NDUFS4 POLR3F PRKN PSMG1 RBX1 RC3H1 RC3H2 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRAPPC10 TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4	8 interacting genes: BRCA1 GATD3 IDS PRKAR1B PSMG2 RRP1 SPRR2A UBE2G2
Entrez ID		7327	8624
HPRD ID		04387	05598
Ensembl ID		ENSG00000184787	ENSG00000183527
Uniprot IDs		P60604	O95456
PDB IDs		2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?
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