UBXN8 and SPCS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UBXN8	SPCS1
Description		UBX domain protein 8	signal peptidase complex subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleoplasm Nucleolus Endoplasmic Reticulum Integral Component Of Endoplasmic Reticulum Membrane	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	Molecular_function Protein Binding Peptidase Activity
	Biological Process	Single Fertilization Ubiquitin-dependent ERAD Pathway	Signal Peptide Processing Proteolysis Virion Assembly Viral Protein Processing Protein Targeting To ER
Pathways			SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Feeling worry ( 29500382) Schizophrenia ( 28991256 25056061 29483656 23974872) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		13 interacting genes: ADRB3 AQP6 C8orf86 DCTN6 GJA8 HSD17B13 MEOX2 PGRMC2 RBPMS SFRP1 SPCS1 TMEM14B WRN	10 interacting genes: AQP2 FIS1 FXYD6-FXYD2 NAALAD2 RPRM SLC22A2 SLC25A46 TMEM74 UBXN8 YIPF2
Entrez ID		7993	28972
HPRD ID		03692	07155
Ensembl ID		ENSG00000104691	ENSG00000114902
Uniprot IDs		B4DKK1 O00124	Q9Y6A9
PDB IDs
Enriched GO Terms of Interacting Partners?
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