CYBRD1 and SERP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYBRD1	SERP2
Description		cytochrome b reductase 1	stress associated endoplasmic reticulum protein family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane Extracellular Exosome	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Metal Ions Identical Protein Binding Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity Transmembrane Monodehydroascorbate Reductase Activity	Protein Binding
	Biological Process	Cellular Iron Ion Homeostasis Response To Iron Ion Reductive Iron Assimilation Iron Ion Homeostasis Transmembrane Transport Ascorbate Homeostasis	Protein Glycosylation Protein Transport Endoplasmic Reticulum Unfolded Protein Response
Pathways		Iron uptake and transport
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Pulse pressure ( 30224653) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Chronic obstructive pulmonary disease ( 30804561) Dupuytren's disease ( 28886342) Fasting insulin (dietary factor interaction) ( 24204828) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828)
Interacting Genes		20 interacting genes: CREB3 FKBP8 GIMAP5 GOSR2 HMOX1 LMNA LPAR3 NEDD4L PLP2 RABAC1 SEC22A SERP1 SERP2 STX4 STX7 TMEM120A TMEM65 VAPA VAPB ZFPL1	52 interacting genes: ALG10 AQP6 BIK BSCL2 CERS4 CISD2 CKB CYB561 CYBRD1 EBP ELOVL4 ERGIC3 EWSR1 FAM210B FCGR2A FNDC9 FRMD3 GET1 GKN1 GPR152 GPR42 KASH5 LHFPL5 LMNA LYVE1 MFSD14B MTIF3 MUC1 NEMP1 OPRM1 PTGES RETREG3 RNASEK SCN3B SLC10A6 SLC30A4 SLC38A1 SLC38A7 SPACA1 STOM STX1A TIMMDC1 TM4SF18 TM4SF19 TMED8 TMEM106C TMEM14B TMEM179B TMEM237 TMEM31 TMEM80 TMX2
Entrez ID		79901	387923
HPRD ID		05764	16590
Ensembl ID		ENSG00000071967	ENSG00000151778
Uniprot IDs		Q53TN4	Q8N6R1
PDB IDs		5ZLE 5ZLG
Enriched GO Terms of Interacting Partners?
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