CYBRD1 and LPAR3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYBRD1	LPAR3
Description		cytochrome b reductase 1	lysophosphatidic acid receptor 3
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane Extracellular Exosome	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Axon Synapse
	Molecular Function	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Metal Ions Identical Protein Binding Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity Transmembrane Monodehydroascorbate Reductase Activity	G-protein Alpha-subunit Binding G Protein-coupled Receptor Activity Protein Binding Phospholipid Binding Lipid Binding Lysophosphatidic Acid Receptor Activity
	Biological Process	Cellular Iron Ion Homeostasis Response To Iron Ion Reductive Iron Assimilation Iron Ion Homeostasis Transmembrane Transport Ascorbate Homeostasis	G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemical Synaptic Transmission Regulation Of Metabolic Process Bleb Assembly Positive Regulation Of MAPK Cascade Positive Regulation Of Collateral Sprouting Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Positive Regulation Of Calcium Ion Transport
Pathways		Iron uptake and transport	G alpha (q) signalling events G alpha (i) signalling events Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Pulse pressure ( 30224653) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Dental caries ( 23064961) Glucose homeostasis traits ( 25524916) Heel bone mineral density ( 30598549) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
Interacting Genes		20 interacting genes: CREB3 FKBP8 GIMAP5 GOSR2 HMOX1 LMNA LPAR3 NEDD4L PLP2 RABAC1 SEC22A SERP1 SERP2 STX4 STX7 TMEM120A TMEM65 VAPA VAPB ZFPL1	58 interacting genes: APP AQP6 ARL13B ASZ1 BCL2L13 C16orf54 CD53 CD74 CD79A CLDN2 CLDN7 CLDN9 CLEC12B CPLX4 CREB3L1 CYB561 CYBRD1 EDA ERGIC3 FAM209A FAM210B FFAR2 FNDC9 GJB5 GNAI2 GORAB GPX8 JAGN1 KCNC1 KCNJ6 LEPROTL1 LHFPL5 LIME1 LMNA MFF MGST3 MRM1 MS4A4A NDUFAF2 OPRM1 PGRMC2 RELL2 RETREG3 SCN3B SGMS2 SHISAL1 SLC10A6 SLC16A2 SLC35C2 TFEC THAP4 TMEM14B TMEM237 TMEM31 TMEM41A TMEM52B TMEM70 TMEM79
Entrez ID		79901	23566
HPRD ID		05764	05486
Ensembl ID		ENSG00000071967	ENSG00000171517
Uniprot IDs		Q53TN4	Q9UBY5
PDB IDs		5ZLE 5ZLG
Enriched GO Terms of Interacting Partners?
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