CYBRD1 and TMEM65

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYBRD1	TMEM65
Description		cytochrome b reductase 1	transmembrane protein 65
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane Extracellular Exosome	Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Intercalated Disc Integral Component Of Membrane
	Molecular Function	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Metal Ions Identical Protein Binding Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity Transmembrane Monodehydroascorbate Reductase Activity	Protein Binding
	Biological Process	Cellular Iron Ion Homeostasis Response To Iron Ion Reductive Iron Assimilation Iron Ion Homeostasis Transmembrane Transport Ascorbate Homeostasis	Cardiac Ventricle Development Regulation Of Cardiac Conduction
Pathways		Iron uptake and transport
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Pulse pressure ( 30224653) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Fear of minor pain ( 28701861)
Interacting Genes		20 interacting genes: CREB3 FKBP8 GIMAP5 GOSR2 HMOX1 LMNA LPAR3 NEDD4L PLP2 RABAC1 SEC22A SERP1 SERP2 STX4 STX7 TMEM120A TMEM65 VAPA VAPB ZFPL1	33 interacting genes: ABHD16A AQP6 ARL13B CYB561 CYBRD1 EBP ERGIC3 FAM174A FAM209A GJA8 GPR42 HSD17B11 IGSF9 IL3RA JAGN1 JPH1 LMNA MSMO1 PDZK1IP1 PTGES PVR REEP4 RETREG3 SCN3B SLC10A6 SLC18A1 SLC35C2 SLC7A8 TIMMDC1 TMEM101 TMEM80 TMX2 ZFYVE27
Entrez ID		79901	157378
HPRD ID		05764	14102
Ensembl ID		ENSG00000071967	ENSG00000164983
Uniprot IDs		Q53TN4	Q6PI78
PDB IDs		5ZLE 5ZLG
Enriched GO Terms of Interacting Partners?
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