HDAC11 and NUP210

		HDAC11	NUP210
Description		histone deacetylase 11	nucleoporin 210
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Plasma Membrane	Nuclear Envelope Nuclear Pore Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Histone Deacetylase Activity Protein Binding NAD-dependent Histone Deacetylase Activity (H3-K14 Specific) DNA-binding Transcription Factor Binding	Protein Binding
	Biological Process	Chromatin Organization Oligodendrocyte Development Histone Deacetylation Histone H3 Deacetylation	Protein Transport MRNA Transport Protein-containing Complex Assembly
Pathways		NOTCH1 Intracellular Domain Regulates Transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway	ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events
Drugs		Belinostat Panobinostat
Diseases
GWAS		Body mass index ( 26426971) Height ( 20881960) Hip circumference adjusted for BMI ( 34021172 25673412) Ulcerative colitis ( 26278503) Waist circumference adjusted for body mass index ( 34021172)	Coronary artery disease in type 1 diabetes ( 29695241)
Interacting Genes		9 interacting genes: CDC25A CDKN1A HDAC6 MAPK6 MRPS25 NELFCD NRM NUP210 PHYHIP	8 interacting genes: ADGRG2 CDK1 EXOSC5 HDAC11 MTDH TMEM40 TRIP6 TSEN2
Entrez ID		79885	23225
HPRD ID		09146	06368
Ensembl ID		ENSG00000163517	ENSG00000132182
Uniprot IDs		B5MCQ6 E7ETT9 Q6IA14 Q96DB2	Q8TEM1
PDB IDs
Enriched GO Terms of Interacting Partners?
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