HDAC11 and PHYHIP

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HDAC11	PHYHIP
Description		histone deacetylase 11	phytanoyl-CoA 2-hydroxylase interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Plasma Membrane	Cytoplasm
	Molecular Function	Histone Deacetylase Activity Protein Binding NAD-dependent Histone Deacetylase Activity (H3-K14 Specific) DNA-binding Transcription Factor Binding	Protein Tyrosine Kinase Binding
	Biological Process	Chromatin Organization Oligodendrocyte Development Histone Deacetylation Histone H3 Deacetylation	Protein Localization
Pathways		NOTCH1 Intracellular Domain Regulates Transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway
Drugs		Belinostat Panobinostat
Diseases
GWAS		Body mass index ( 26426971) Height ( 20881960) Hip circumference adjusted for BMI ( 34021172 25673412) Ulcerative colitis ( 26278503) Waist circumference adjusted for body mass index ( 34021172)	Hypertriglyceridemia ( 23505323)
Interacting Genes		9 interacting genes: CDC25A CDKN1A HDAC6 MAPK6 MRPS25 NELFCD NRM NUP210 PHYHIP	24 interacting genes: ADGRB1 COPS6 DYRK1A EEF1A1 ERG28 FAM131A HDAC11 HNRNPA1 MAGED4B MED8 METTL18 NDRG1 NDUFV3 NFE2 PHYH PNPLA2 PPIE PRMT5 S100A13 SMARCC2 SUPT5H TTR WDR89 ZZEF1
Entrez ID		79885	9796
HPRD ID		09146	16345
Ensembl ID		ENSG00000163517	ENSG00000168490
Uniprot IDs		B5MCQ6 E7ETT9 Q6IA14 Q96DB2	Q92561
PDB IDs
Enriched GO Terms of Interacting Partners?
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