NUP210 and HDAC11

		NUP210	HDAC11
Description		nucleoporin 210	histone deacetylase 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Nuclear Membrane	Histone Deacetylase Complex Nucleus Plasma Membrane
	Molecular Function	Protein Binding	Histone Deacetylase Activity Protein Binding NAD-dependent Histone Deacetylase Activity (H3-K14 Specific) DNA-binding Transcription Factor Binding
	Biological Process	Protein Transport MRNA Transport Protein-containing Complex Assembly	Chromatin Organization Oligodendrocyte Development Histone Deacetylation Histone H3 Deacetylation
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events	NOTCH1 Intracellular Domain Regulates Transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway
Drugs			Belinostat Panobinostat
Diseases
GWAS		Coronary artery disease in type 1 diabetes ( 29695241)	Body mass index ( 26426971) Height ( 20881960) Hip circumference adjusted for BMI ( 34021172 25673412) Ulcerative colitis ( 26278503) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		8 interacting genes: ADGRG2 CDK1 EXOSC5 HDAC11 MTDH TMEM40 TRIP6 TSEN2	9 interacting genes: CDC25A CDKN1A HDAC6 MAPK6 MRPS25 NELFCD NRM NUP210 PHYHIP
Entrez ID		23225	79885
HPRD ID		06368	09146
Ensembl ID		ENSG00000132182	ENSG00000163517
Uniprot IDs		Q8TEM1	B5MCQ6 E7ETT9 Q6IA14 Q96DB2
PDB IDs
Enriched GO Terms of Interacting Partners?
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