CCDC134 and PGRMC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCDC134	PGRMC1
Description		coiled-coil domain containing 134	progesterone receptor membrane component 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Endoplasmic Reticulum Membrane	Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse
	Molecular Function	Protein Binding	Amyloid-beta Binding Steroid Binding Protein Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Angiogenesis Placenta Development Ventricular System Development Embryonic Hemopoiesis Embryonic Liver Development	Heme Biosynthetic Process
Pathways			Neutrophil degranulation
Drugs			Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Alzheimer's disease biomarkers ( 21123754) Intelligence (MTAG) ( 29326435) Meat-related diet ( 32066663) Plateletcrit ( 32888494) Processed meat consumption ( 32066663) Refractive error ( 32231278)	Hodgkin's lymphoma ( 34216518)
Interacting Genes		5 interacting genes: CENPM PGRMC1 PTPRN TADA2A UBQLN4	21 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 MTNR1A MX1 PAM16 PGRMC2 SCAP SGTB TMEM213 ZNF71
Entrez ID		79879	10857
HPRD ID		07988	02338
Ensembl ID		ENSG00000100147	ENSG00000101856
Uniprot IDs		B0QY51 B4DRL0 Q9H6E4	O00264 Q6IB11
PDB IDs			4X8Y
Enriched GO Terms of Interacting Partners?
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