PRRC2A and MAD2L2

Number of citations of the paper that reports this interaction (PubMedID 14667819)
36

Data Source:
HPRD (two hybrid)

		PRRC2A	MAD2L2
Description		proline rich coiled-coil 2A	mitotic arrest deficient 2 like 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Membrane Extracellular Exosome	Nucleus Nucleoplasm Chromosome Nucleolus Spindle Cytosol Zeta DNA Polymerase Complex Site Of Double-strand Break
	Molecular Function	RNA Binding Protein Binding	Protein Binding JUN Kinase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Growth Double-strand Break Repair Actin Filament Organization Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription By Competitive Promoter Binding Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Protein Catabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Isotype Switching Positive Regulation Of Transcription, DNA-templated Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Ubiquitin Protein Ligase Activity Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways			Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 34211149) Anxiety ( 33859377) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Body shape index ( 34021172) Childhood body mass index ( 33045005) Hand grip strength ( 29691431) Height ( 28552196) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Leukocyte telomere length ( 32109421) Malaria ( 31844061) Menopause (age at onset) ( 22267201) Metabolite levels ( 31628463) Platelet distribution width ( 32888494) Schizophrenia ( 23894747) Systolic blood pressure ( 30578418) Ulcerative colitis ( 28067908) Waist circumference ( 31928498) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		28 interacting genes: ATN1 ATXN1 C1QBP CCR10 CPSF1 DDX20 EIF3E EWSR1 FGA GANAB GORASP2 GRB2 HNRNPA1 HNRNPM IFT88 IMMT JUN MAD2L2 MAN2C1 P4HA2 PRMT2 PSMA3 QARS1 RBFOX1 RERE SRPK2 SSR3 UBAP2L	48 interacting genes: ADAM15 ADAM17 ADAM9 C20orf85 CAMK2B CDC20 CDH1 DEPDC5 ELK1 FAM217B FTO FZR1 GSC2 IKZF1 IKZF3 INCA1 KCTD9 KRT34 MAD2L1 MAD2L1BP MBD3L1 MYBPC2 PIGV PLAGL2 POLDIP2 PPM1B PRCC PRR5L PRRC2A RAB11FIP4 RBBP6 REL REV1 REV3L SFI1 SHLD1 TCF4 THAP6 TRIM27 TRIM54 TRIM7 YPEL3 YY1AP1 ZBED1 ZMYND12 ZNF511 ZNF558 ZNF655
Entrez ID		7916	10459
HPRD ID		00807	07246
Ensembl ID		ENSG00000204469	ENSG00000116670
Uniprot IDs		A0A1U9X974 P48634	A0A024R4I4 Q9UI95
PDB IDs			3ABD 3ABE 3VU7 4EXT 4GK0 4GK5 5XPT 5XPU 6BC8 6BCD 6BI7 6K07 6K08 6KEA 6KTO 6M7A 6M7B 6NIF 6VE5 6WS0 6WS5 6WW9 6WWA 7L9P
Enriched GO Terms of Interacting Partners?
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