MAD2L2 and PIGV

		MAD2L2	PIGV
Description		mitotic arrest deficient 2 like 2	phosphatidylinositol glycan anchor biosynthesis class V
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Spindle Cytosol Zeta DNA Polymerase Complex Site Of Double-strand Break	Endoplasmic Reticulum Membrane Integral Component Of Membrane Mannosyltransferase Complex
	Molecular Function	Protein Binding JUN Kinase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Alpha-1,6-mannosyltransferase Activity Mannosyltransferase Activity Glycolipid Mannosyltransferase Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Growth Double-strand Break Repair Actin Filament Organization Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription By Competitive Promoter Binding Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Protein Catabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Isotype Switching Positive Regulation Of Transcription, DNA-templated Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Ubiquitin Protein Ligase Activity Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining	GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane Mannosylation
Pathways		Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI	Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Visceral adipose tissue adjusted for BMI ( 22589738)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Blond vs. brown/black hair color ( 30531825) Blood protein levels in cardiovascular risk ( 28369058) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899) LDL cholesterol ( 24097068 25961943) LDL cholesterol levels ( 28334899) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 27863252) Sum basophil neutrophil counts ( 27863252) Triglyceride levels ( 28334899 32154731) Triglycerides ( 24097068)
Interacting Genes		48 interacting genes: ADAM15 ADAM17 ADAM9 C20orf85 CAMK2B CDC20 CDH1 DEPDC5 ELK1 FAM217B FTO FZR1 GSC2 IKZF1 IKZF3 INCA1 KCTD9 KRT34 MAD2L1 MAD2L1BP MBD3L1 MYBPC2 PIGV PLAGL2 POLDIP2 PPM1B PRCC PRR5L PRRC2A RAB11FIP4 RBBP6 REL REV1 REV3L SFI1 SHLD1 TCF4 THAP6 TRIM27 TRIM54 TRIM7 YPEL3 YY1AP1 ZBED1 ZMYND12 ZNF511 ZNF558 ZNF655	5 interacting genes: MAD2L2 MADCAM1 MTFR1L PITHD1 ZNF593
Entrez ID		10459	55650
HPRD ID		07246	07912
Ensembl ID		ENSG00000116670	ENSG00000060642
Uniprot IDs		A0A024R4I4 Q9UI95	Q9NUD9
PDB IDs		3ABD 3ABE 3VU7 4EXT 4GK0 4GK5 5XPT 5XPU 6BC8 6BCD 6BI7 6K07 6K08 6KEA 6KTO 6M7A 6M7B 6NIF 6VE5 6WS0 6WS5 6WW9 6WWA 7L9P
Enriched GO Terms of Interacting Partners?
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