PRRC2A and DDX20

Number of citations of the paper that reports this interaction (PubMedID 14667819)
36

Data Source:
HPRD (two hybrid)

		PRRC2A	DDX20
Description		proline rich coiled-coil 2A	DEAD-box helicase 20
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane SMN Complex SMN-Sm Protein Complex RNA Polymerase II Transcription Repressor Complex Gemini Of Coiled Bodies
	Molecular Function	RNA Binding Protein Binding	DNA Binding RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Histone Deacetylase Binding DNA-binding Transcription Factor Binding
	Biological Process	Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Oogenesis Regulation Of Steroid Biosynthetic Process
Pathways			snRNP Assembly
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 34211149) Anxiety ( 33859377) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Body shape index ( 34021172) Childhood body mass index ( 33045005) Hand grip strength ( 29691431) Height ( 28552196) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Leukocyte telomere length ( 32109421) Malaria ( 31844061) Menopause (age at onset) ( 22267201) Metabolite levels ( 31628463) Platelet distribution width ( 32888494) Schizophrenia ( 23894747) Systolic blood pressure ( 30578418) Ulcerative colitis ( 28067908) Waist circumference ( 31928498) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Body mass index ( 29273807) Metabolite levels ( 23823483) Venous thromboembolism ( 32232851)
Interacting Genes		28 interacting genes: ATN1 ATXN1 C1QBP CCR10 CPSF1 DDX20 EIF3E EWSR1 FGA GANAB GORASP2 GRB2 HNRNPA1 HNRNPM IFT88 IMMT JUN MAD2L2 MAN2C1 P4HA2 PRMT2 PSMA3 QARS1 RBFOX1 RERE SRPK2 SSR3 UBAP2L	32 interacting genes: AGO2 APP CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 NCOR1 NCOR2 NR0B2 NUFIP1 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3 TP53
Entrez ID		7916	11218
HPRD ID		00807	05859
Ensembl ID		ENSG00000204469	ENSG00000064703
Uniprot IDs		A0A1U9X974 P48634	Q9H4N4 Q9UHI6
PDB IDs			2OXC 3B7G
Enriched GO Terms of Interacting Partners?
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