FA2H and ARMC12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FA2H	ARMC12
Description		fatty acid 2-hydroxylase	armadillo repeat containing 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Nucleus
	Molecular Function	Iron Ion Binding Protein Binding Heme Binding Fatty Acid Alpha-hydroxylase Activity
	Biological Process	Sebaceous Gland Cell Differentiation Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Glucosylceramide Biosynthetic Process Galactosylceramide Biosynthetic Process Sphingolipid Biosynthetic Process Lipid Modification Central Nervous System Myelin Maintenance Peripheral Nervous System Myelin Maintenance Regulation Of Cell Population Proliferation Regulation Of Hair Cycle Plasma Membrane Raft Organization Ceramide Biosynthetic Process Establishment Of Skin Barrier
Pathways		Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		General cognitive ability ( 25383866) Pancreatic cancer ( 25086665) White matter lesion progression (adjusted for white matter lesion burden at baseline) ( 26451028)	Depression x herpes simplex 1 infection interaction ( 32564518) Eosinophil percentage of granulocytes ( 27863252) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		31 interacting genes: AQP6 ARMC12 ASGR2 CD79A CREB3 CREB3L1 DLG2 EBP ELOVL4 ERGIC3 ERLIN1 FAM209A FCER1G GPR152 GPR37 GPX8 LMNA MARCHF8 MSR1 PEX12 PGRMC2 RIC3 SGPL1 SLC10A1 SLC10A6 SYT2 TLCD4 TMEM14B TMEM41A TMX2 UBQLN4	8 interacting genes: EHHADH FA2H GAD2 RBBP4 SENP2 SNX1 SPG21 TTPA
Entrez ID		79152	221481
HPRD ID		16873	12901
Ensembl ID		ENSG00000103089	ENSG00000157343
Uniprot IDs		Q7L5A8	Q5T9G4
PDB IDs
Enriched GO Terms of Interacting Partners?
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