PHF21A and HMG20A

Number of citations of the paper that reports this interaction (PubMedID 26496610)
430

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down)

		PHF21A	HMG20A
Description		PHD finger protein 21A	high mobility group 20A
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm DNA Repair Complex	Nucleus
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Metal Ion Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation
Pathways		HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Axial length ( 24144296) Height ( 29782485) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Menarche (age at onset) ( 21102462 25231870) Refractive error ( 32231278) Serum metabolite levels ( 33031748) Triglyceride levels ( 32203549) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172)	Fasting glucose ( 33402679 34059833) Glycated hemoglobin levels ( 34059833) Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 22885922 24509480 30054458 22693455 21874001 30297969 32499647 30718926 28869590)
Interacting Genes		18 interacting genes: BANP EXOSC8 FHL2 FHL3 H3C14 HDAC1 HDAC2 HMG20A HMG20B KDM1A KRT40 L3MBTL3 LPXN NUP62 RCOR1 SP3 TRAF1 ZYX	60 interacting genes: ADD1 AGR2 BACH2 BRAP C9orf72 CCDC136 CCNK CEP95 CFAP53 CREBBP DCTN4 DDIT4L DGCR6L DTNA DTNB FBXO7 FMNL1 FOXD4L1 FXR1 GADD45GIP1 GPSM1 GTF2A1L HMG20B HPCAL1 KIFC3 KPNA2 KRT1 LMO1 LNX1 LURAP1 MAGOHB NTAQ1 NUTF2 OLIG3 PHF21A PIAS2 PICK1 PSMB1 PSORS1C2 PSTPIP1 PTH2R QARS1 RAD54L2 RBM7 RIN1 RPP30 RPRD1B RSPH9 RUSC1 SCNM1 SMAD4 SMYD1 SUOX SYTL4 TBC1D22B TCP11L1 TESC TRAF4 TRAPPC5 USHBP1
Entrez ID		51317	10363
HPRD ID		10516	16116
Ensembl ID		ENSG00000135365	ENSG00000140382
Uniprot IDs		Q96BD5	B4DMG1 Q9NP66
PDB IDs		2PUY 2YQL
Enriched GO Terms of Interacting Partners?
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