ZAP70 and PTPN6

  • Number of citations of the paper that reports this interaction (PubMedID 8638162)
  • 88
  • Data Source:
  • HPRD (in vitro)

ZAP70

PTPN6

Description zeta chain of T cell receptor associated protein kinase 70 protein tyrosine phosphatase non-receptor type 6
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Mean corpuscular hemoglobin concentration ( 29403010)
  • Red blood cell fatty acid levels ( 25500335)
  • Refractive error ( 32231278)
Interacting Genes 67 interacting genes: ABL1 ACP1 ANAPC11 APP ASB3 CARD11 CBL CBLB CBLC CD247 CD3E CD5 CD79B CRK CSK CUL3 DAPK1 DBNL DEF6 DUSP3 EGFR ERBB2 ERBB3 ERBB4 FCGR3A FCRL3 FYN GAB2 GRB2 IFNAR1 KIT LAT LAX1 LCK LCP2 LRRK2 MET MUC1 NDUFB8 NFAM1 NR0B2 PAG1 PLCG1 PRLR PTK2B PTPN22 PTPN3 PTPN6 PTPRC RASA1 RNF41 SH2B3 SH3BP2 SHB SHC1 SIT1 SLA SLA2 SLAMF6 SOS1 TUBA1A TUBA4A TUBB TYROBP USP2 VAV1 WIPF1 115 interacting genes: AATK ABL1 ACTN1 ACTN4 BCR BLNK BTLA CAV1 CBL CCDC88A CD22 CD247 CD300LF CD33 CD5 CD72 CD79A CD79B CDK1 CEACAM1 CLEC4A CSF2RB CTNNB1 CTNND1 CUZD1 CXCR4 DOK1 EGFR EPOR ERBB2 ERBB3 ERBB4 ESR1 FAS FCGR2B FCRL3 FGFR4 FHL3 FLT3 GAB2 GHR GRB2 HOXA10 IFNAR1 IGF1R IL2RB IL4R IL6ST INSR IRS2 IRS4 JAK1 JAK2 JAK3 KDR KHDRBS1 KIR2DL3 KIR2DL5A KIT KLRA1P KLRB1 KLRC1 LAIR1 LAT LCK LCP2 LIFR LILRB2 LILRB4 LMTK2 LYN MPIG6B MS4A2 MYH9 NOS1 OLIG1 PAG1 PDGFRB PECAM1 PIK3R1 PILRA PILRB PLCG2 PRKCA PRKCD PTK2B PTK7 PTPN11 PTPRC ROR1 ROR2 ROS1 SHC1 SIGLEC10 SIGLEC11 SIGLEC12 SIRPA SLAMF6 SOS1 SPATA2 SRC SSTR2 STAT5B STAT6 SYK TFG TLR10 TMEM62 TNFRSF1A TRAF3 TRAF6 TREML1 TYK2 VAV1 ZAP70
Entrez ID 7535 5777
HPRD ID 01495 01475
Ensembl ID ENSG00000115085 ENSG00000111679
Uniprot IDs P43403 P29350 Q53XS4
PDB IDs 1FBV 1M61 1U59 2CBL 2OQ1 2OZO 2Y1N 3ZNI 4A4B 4A4C 4K2R 4XZ0 4XZ1 5O76 1FPR 1GWZ 1X6C 2B3O 2RMX 2YU7 3PS5 4GRY 4GRZ 4GS0 4HJP 4HJQ 6SM5
Enriched GO Terms of Interacting Partners?
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