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VAV2 and SNW1
Number of citations of the paper that reports this interaction (PubMedID
18654987
)
21
Data Source:
BioGRID
(two hybrid)
VAV2
SNW1
Description
vav guanine nucleotide exchange factor 2
SNW domain containing 1
Image
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Chromatin
Nucleus
Nucleoplasm
Spliceosomal Complex
Cytoplasm
Nuclear Matrix
Nuclear Body
Nuclear Speck
U2-type Catalytic Step 2 Spliceosome
Catalytic Step 2 Spliceosome
SMAD Protein Complex
Molecular Function
Phosphotyrosine Residue Binding
Guanyl-nucleotide Exchange Factor Activity
Epidermal Growth Factor Receptor Binding
Protein Binding
Metal Ion Binding
Transcription Coactivator Activity
Transcription Corepressor Activity
RNA Binding
Notch Binding
Protein Binding
Nuclear Receptor Binding
Enzyme Binding
Vitamin D Receptor Binding
Retinoic Acid Receptor Binding
SMAD Binding
Androgen Receptor Binding
Biological Process
Angiogenesis
Signal Transduction
Small GTPase Mediated Signal Transduction
Regulation Of Cell Size
Cell Migration
Lamellipodium Assembly
Platelet Activation
Fc-epsilon Receptor Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Regulation Of GTPase Activity
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Negative Regulation Of Transcription By RNA Polymerase II
MRNA Splicing, Via Spliceosome
Regulation Of Transcription By RNA Polymerase II
Schwann Cell Proliferation
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Positive Regulation By Host Of Viral Transcription
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of MRNA Splicing, Via Spliceosome
Retinoic Acid Receptor Signaling Pathway
Regulation Of Retinoic Acid Receptor Signaling Pathway
Positive Regulation Of Neurogenesis
Positive Regulation Of Histone H3-K4 Methylation
Regulation Of Vitamin D Receptor Signaling Pathway
Positive Regulation Of Vitamin D Receptor Signaling Pathway
Cellular Response To Retinoic Acid
Pathways
GPVI-mediated activation cascade
GPVI-mediated activation cascade
NRAGE signals death through JNK
Regulation of actin dynamics for phagocytic cup formation
DAP12 signaling
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated Ca+2 mobilization
EPH-ephrin mediated repulsion of cells
G alpha (12/13) signalling events
VEGFA-VEGFR2 Pathway
VEGFA-VEGFR2 Pathway
Signal transduction by L1
VEGFR2 mediated vascular permeability
RHOA GTPase cycle
RHOB GTPase cycle
RHOC GTPase cycle
CDC42 GTPase cycle
RAC1 GTPase cycle
RAC2 GTPase cycle
RHOG GTPase cycle
RAC3 GTPase cycle
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Pre-NOTCH Transcription and Translation
Pre-NOTCH Transcription and Translation
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
NOTCH1 Intracellular Domain Regulates Transcription
NOTCH1 Intracellular Domain Regulates Transcription
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Notch-HLH transcription pathway
mRNA Splicing - Major Pathway
RUNX3 regulates NOTCH signaling
RUNX3 regulates NOTCH signaling
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH4 Intracellular Domain Regulates Transcription
Drugs
Diseases
GWAS
Central corneal thickness (
29760442
)
Corneal astigmatism (
30306274
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Hematocrit (
27863252
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Multiple sclerosis (
20598377
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Red blood cell count (
32888494
)
vWF and FVIII levels (
21810271
)
Response to platinum-based chemotherapy in non-small-cell lung cancer (
22872573
)
Interacting Genes
70 interacting genes:
AR
ARIH1
BIRC6
BOD1L1
BRDT
BZW1
CAV1
CBL
CBLB
CCNO
CCT2
CCT3
CD19
CD44
CEP170
CHMP3
CIZ1
CRCP
DCUN1D4
DNAJC21
EGFR
EIF4G3
EPHB2
ERBB2
ERBB3
ERBB4
FNTA
FUCA1
FYN
GAB1
GAPVD1
GRB2
HNRNPF
HSPH1
IPO4
MED21
MET
MRGBP
NCKAP5
NEK3
NUP214
PHF10
PNMA1
POGZ
PPM1B
PRLR
PRRG4
RAC1
RAD23A
RBBP6
RHOA
RHOG
SERBP1
SF3A3
SH3BP2
SNW1
SOCS1
SRPK2
SRRT
ST13
STK24
STOM
SYK
TARBP2
TCP11
TOM1L1
TTN
UBE4B
USP38
VCPIP1
98 interacting genes:
ABLIM3
ACTN2
ASCC2
BICD2
BYSL
C1orf216
CCDC125
CEP55
CEP70
CIR1
CWF19L2
DAXX
EP300
ERCC3
EXOSC5
FAM90A1
GABPB1
GAS2L2
GOLGA2
GRIPAP1
HDAC2
HMBOX1
HOOK2
HSF2BP
IKBKG
IKZF1
JDP2
KANK2
KRT40
LRP2BP
LZTS2
MAGEA1
MAGOHB
MAPK6
MCMBP
MEN1
MFAP1
MISP
MSL1
MTUS2
NCK2
NCOA1
NCOR1
NCOR2
NOTCH1
NOTCH3
NR0B1
NR0B2
NXF1
OCLN
ODF2
OGT
OSTF1
PABPN1
PCBD2
PGR
PICK1
PPIL1
PRKAA2
PRKAR1B
RABEP1
RARA
RB1
RBL1
RBL2
RBPJ
RINT1
RXRA
SAAL1
SART1
SIN3A
SIRT1
SKI
SMAD2
SMAD3
SMAD4
SNRNP200
SNU13
SPECC1L
STEEP1
SUMO2
TCP11L1
TEX11
TFIP11
TNNT1
TOP1
TRAF1
TRIM15
TRIM23
TRIM55
TRIM63
TTC14
USF1
VAV2
VDR
VPS39
WBP4
ZSCAN1
Entrez ID
7410
22938
HPRD ID
02694
04340
Ensembl ID
ENSG00000160293
ENSG00000100603
Uniprot IDs
P52735
G3V3A4
Q13573
PDB IDs
2DLZ
2DM1
2LNW
2LNX
4ROJ
5MQF
5XJC
5YZG
5Z58
6FF4
6FF7
6ICZ
6ID0
6ID1
6QDV
6ZYM
7A5P
7AAV
7ABF
7ABG
7ABI
Enriched GO Terms of Interacting Partners
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