UBE2G1 and RC3H1

Number of citations of the paper that reports this interaction (PubMedID 26489670)
13

Data Source:
BioGRID (pull down)

		UBE2G1	RC3H1
Description		ubiquitin conjugating enzyme E2 G1	ring finger and CCCH-type domains 1
Image
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	P-body Cytoplasmic Stress Granule
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	RNA Binding Double-stranded RNA Binding MRNA Binding MRNA 3'-UTR Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding MiRNA Binding RNA Stem-loop Binding Ubiquitin Protein Ligase Activity CCR4-NOT Complex Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination	Protein Polyubiquitination Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process B Cell Homeostasis Regulation Of Germinal Center Formation Negative Regulation Of Germinal Center Formation Ubiquitin-dependent Protein Catabolic Process Posttranscriptional Regulation Of Gene Expression Negative Regulation Of B Cell Proliferation P-body Assembly T Cell Proliferation T Cell Homeostasis Regulation Of MRNA Stability Negative Regulation Of T-helper Cell Differentiation Negative Regulation Of Activated T Cell Proliferation Lymph Node Development Spleen Development T Cell Receptor Signaling Pathway Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization T Follicular Helper Cell Differentiation Cellular Response To Interleukin-1 Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of T-helper 17 Cell Differentiation Regulation Of MiRNA Metabolic Process
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Plasma trimethylamine N-oxide levels ( 28439531) Refractive error ( 32231278) Schizophrenia ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Small cell lung carcinoma ( 28604730)
Interacting Genes		20 interacting genes: AMFR APP CBL CUL9 DIO2 FBXL2 HUWE1 ITCH MAP3K1 MARCHF6 PRKN RBCK1 RBX1 RC3H1 SMURF1 SYVN1 TRIM63 UBA1 UBE2E1 UBE3A	14 interacting genes: ICOS TNF TNFRSF4 UBE2A UBE2B UBE2D2 UBE2F UBE2G1 UBE2G2 UBE2L3 UBE2N UBE2V1 UBE2V2 UCP3
Entrez ID		7326	149041
HPRD ID		03340	13913
Ensembl ID		ENSG00000132388	ENSG00000135870
Uniprot IDs		P62253	B7ZMB3 B9EGU6 Q5TC82
PDB IDs		2AWF 6D68	3X1O 4QIK 4QIL 4ULW 4YWQ
Enriched GO Terms of Interacting Partners?
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