TNR and PTPRZ1

Number of citations of the paper that reports this interaction (PubMedID 9507007)
33

Data Source:
BioGRID (pull down)

		TNR	PTPRZ1
Description		tenascin R	protein tyrosine phosphatase receptor type Z1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Surface Membrane Raft Collagen-containing Extracellular Matrix Perineuronal Net Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Intrinsic Component Of Plasma Membrane Synapse Perineuronal Net
	Molecular Function	Signaling Receptor Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Integrin Binding Protein Binding
	Biological Process	Cell Adhesion Neuron Cell-cell Adhesion Axon Guidance Associative Learning Telencephalon Cell Migration Negative Regulation Of Cell-cell Adhesion Extracellular Matrix Organization Locomotory Exploration Behavior Negative Regulation Of Axon Extension Involved In Regeneration Negative Regulation Of Synaptic Transmission Synapse Organization Neuromuscular Process Controlling Balance Positive Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Transmission Of Nerve Impulse Long-term Synaptic Potentiation	Hematopoietic Progenitor Cell Differentiation Protein Dephosphorylation Axonogenesis Central Nervous System Development Learning Or Memory Regulation Of Myelination Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Neuron Apoptotic Process Oligodendrocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation
Pathways		ECM proteoglycans	Signaling by ALK Other interleukin signaling
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Attention deficit hyperactivity disorder ( 30563984) Body mass index ( 26426971) Corneal astigmatism ( 29422769) Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644) Liver fibrosis in non-alcoholic fatty liver disease ( 31311600) Sleep (1/2-day periodicity) ( 33075057) Telomere length ( 30185882) Testosterone levels x fluid intelligence interaction ( 33407712) Tonometry ( 17903302)	Hand grip strength ( 27325353) Heel bone mineral density ( 30598549) Lung adenocarcinoma ( 28604730)
Interacting Genes		18 interacting genes: ACAN BCAN CCDC146 CNTN1 LGALS14 MAGEB4 NCAN NCK2 NFASC NTAQ1 POLR3C PSMA1 PTPRZ1 QSOX1 RUNX1 SIGLEC1 TRIM54 VCAN	16 interacting genes: AASS ADD2 ALK ARHGAP35 BMP1 CTNNB1 FYN GIT1 HMGB1 IL34 MDK MGAT5B NMB PTN PTPRF TNR
Entrez ID		7143	5803
HPRD ID		03589	01481
Ensembl ID		ENSG00000116147	ENSG00000106278
Uniprot IDs		A1L306 Q92752	B4DFE7 P23471
PDB IDs			3JXF 3S97 5AWX 5H08
Enriched GO Terms of Interacting Partners?
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