PTPRZ1 and AASS

		PTPRZ1	AASS
Description		protein tyrosine phosphatase receptor type Z1	aminoadipate-semialdehyde synthase
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Intrinsic Component Of Plasma Membrane Synapse Perineuronal Net	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Integrin Binding Protein Binding	Transcription Corepressor Activity Saccharopine Dehydrogenase Activity Saccharopine Dehydrogenase (NAD+, L-lysine-forming) Activity Histone Binding Saccharopine Dehydrogenase (NADP+, L-lysine-forming) Activity Saccharopine Dehydrogenase (NAD+, L-glutamate-forming) Activity
	Biological Process	Hematopoietic Progenitor Cell Differentiation Protein Dephosphorylation Axonogenesis Central Nervous System Development Learning Or Memory Regulation Of Myelination Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Neuron Apoptotic Process Oligodendrocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation	Negative Regulation Of Transcription By RNA Polymerase II Lysine Catabolic Process Lysine Biosynthetic Process Via Aminoadipic Acid Negative Regulation Of Histone Methylation L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine
Pathways		Signaling by ALK Other interleukin signaling	Lysine catabolism
Drugs			Glutamic acid NADH NADPH L-Saccharopine
Diseases
GWAS		Hand grip strength ( 27325353) Heel bone mineral density ( 30598549) Lung adenocarcinoma ( 28604730)	Opioid dependence (time to event) ( 34124712)
Interacting Genes		16 interacting genes: AASS ADD2 ALK ARHGAP35 BMP1 CTNNB1 FYN GIT1 HMGB1 IL34 MDK MGAT5B NMB PTN PTPRF TNR	7 interacting genes: ARF5 CCR6 CHCHD3 FSCN3 OGT PTPRZ1 WASL
Entrez ID		5803	10157
HPRD ID		01481	05489
Ensembl ID		ENSG00000106278	ENSG00000008311
Uniprot IDs		B4DFE7 P23471	A4D0W4 Q9UDR5
PDB IDs		3JXF 3S97 5AWX 5H08	5L76 5L78 5O1N 5O1O 5O1P
Enriched GO Terms of Interacting Partners?
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